Does Metformin make you sleepy?

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Does Metformin make you sleepy?


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Old 06-09-2011, 13:56   #1
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Default Does Metformin make you sleepy?

Hi,

I sometimes need to take a nap after supper, which is also after my 3rd Metformin (850 ea.) of the day. My first thought is-- well my blood sugar is too high, but upon checking it, it's not (at least not always). I have no adverse effects with Metformin and I like it because of some of its beneficial effects, such as appetite suppresant, cardiac protection, and others. But I do find a coincidence in taking it and getting sleepy. I wonder if anyone here taking Metformin has had a similar experience.

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Old 06-09-2011, 14:09   #2
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Since I do have some fatigue issues, I can't lay any of it on metformin. However, it is known to deplete B-12 - perhaps taking a supplement would help.

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Old 06-09-2011, 14:13   #3
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No, but high blood sugars sure do!

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Old 06-09-2011, 14:16   #4
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same I have no issues with metaformin...but I take the slow release one

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Old 06-09-2011, 14:17   #5
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well I don't recall that really... but I'm sleepy a lot so that may explain it. lol. Metformin just gave me bad GI side effects constantly. I did post a link somewhere else earlier on metformin side effects.... there's a few.
Here's the link: metformin (Glucophage, Glucophage XR, Glumetza, Fortamet, Riomet) - drug class, medical uses, medication side effects, and drug interactions by MedicineNet.com
Plus here's a link to an Australian study on it: eMJA: Metformin and serious adverse effects

In particular... dehydration can cause problems when on metformin.... so make sure you're drinking plenty of water.

 
Old 06-09-2011, 14:23   #6
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Quote:
Originally Posted by moon View Post
Since I do have some fatigue issues, I can't lay any of it on metformin. However, it is known to deplete B-12 - perhaps taking a supplement would help.


Thank you for your reply moon; i have actually seen that it depletes B vitamins - maybe 12 as you say. I don't take any vitamins at all, so perhaps i'll start with a one-a-day -- can't do any harm.

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Old 06-09-2011, 17:08   #7
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I also take 3 x 850 of metformin. I take my last dose right before bed, so I am not sure if it makes me extra sleepy or not. I do notice by 10 pm I am nodding off on the couch. I always tell my hubbie don't start a movie after 9 pm because I will fall asleep. I do take extra B 12 every day to adress the depletion issue. Sometimes just the process of eating certain foods can cause certain gut hormones which might make you sleepy. For example foods like Turkey have Trypophan ( sp) which makes you tired.

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Old 06-09-2011, 17:18   #8
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I also take 3 x 850 of metformin. I take my last dose right before bed, so I am not sure if it makes me extra sleepy or not. I do notice by 10 pm I am nodding off on the couch. I always tell my hubbie don't start a movie after 9 pm because I will fall asleep. I do take extra B 12 every day to adress the depletion issue. Sometimes just the process of eating certain foods can cause certain gut hormones which might make you sleepy. For example foods like Turkey have Trypophan ( sp) which makes you tired.
OK jwags -- it may also be the timing of taking the Metformin-- forgetting to take with meal and taking much later for example. But to eliminate the "denial" factor i might have to watch the carbo level of the meal too. Sometimes I do feel tired for no diabetically related reason though; it's a fluctuating blood level it seems. Vitamins -- right! Why have i never believed in vitamins? :-)

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Old 06-09-2011, 17:39   #9
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I used to believe the turkey-tryptophan-sleep thing too years ago when I was dealing with fibromyalgia and trying to use natural sleep remedies. Turned out I would have to eat a lot on an empty stomach ... or any number of other meats, fish and cheeses that have tryptophan in the same, or greater, amounts.

My fibro guru used to bemoan that tryptophan supplements were taken off the market because of (if I remember correctly) one bad batch from a Japanese manufacturer.

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Old 06-09-2011, 17:40   #10
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High BGs make me sleepy and I wonder if this is what you are experiencing after supper. It tends to work that way for me -- biggest meal of the day, relaxing in front of the TV... If it was the Metformin wouldn't you expect a similar effect with the doses earlier in the day?

Not to say that you shouldn't also follow up with the B12 level etc... as advised above

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