Starting Metformin; how long until I see benefits?

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Starting Metformin; how long until I see benefits?


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Old 10-29-2011, 03:03   #1
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Default Starting Metformin; how long until I see benefits?

Started on metformin last night, 500mg x2 daily. Until now, I can never get below 100 without a liver dump shooting it back up into the 120s-130s. When I am at work under stress, it can go into the 190s.

Any idea how long before I should be able to see some effect on my base bg level? Kinda hoping it could lower my "bounce" level about 20 points or so...

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Old 10-29-2011, 03:22   #2
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Met often takes 3-4 weeks to reach full strength blood levels, but that doesn't mean it isn't working in the interim. You may see changes in just a few days. Your dose is a good starting level, and if you get by without gastric side effects, my guess would be you could increase your dosage gradually over time, if you don't see as much improvement as you hoped for. What did your doc say about future increases?

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Old 10-29-2011, 06:52   #3
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He said nothing about future increases yet, I almost had to twist his arm to get met to start with. It wasn't until I started mentioning the 190s from stress that he prescribed it.

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Old 10-29-2011, 07:31   #4
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Howdy, it took about 10 days for me to notice Met working - and my sugars improved over time also.

With stress, one key might be exercise - it's a great stress reducer. If you're not exercising, MAKE THE TIME to do a little every day - it helps stress, insulin-resistance, burns glucose and just makes you feel better.

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Old 10-29-2011, 08:58   #5
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Good for you for <almost> twisting his arm!

Insulin resistance is the hallmark of type 2 diabetes & metformin is the absolute BEST treatment for insulin resistance - bar none. You may have to stand up to him more often if he gets stubborn about this - there's no excuse for withholding the meds that will lower your blood sugar. There are no other oral meds that work as well as met without damaging your pancreas.

But see how you do on the current dosage & cross that bridge when you come to it.

Take care.

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Old 10-29-2011, 12:10   #6
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It can take up to 6 weeks for you to start seeing improvement. I didn't see any improvement at 500 2x's a day dose, so my Doc tested my C-peptide and found out I wasn't producing enough insulin. So, we added Insulin and my numbers are normal now.

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Old 10-29-2011, 12:46   #7
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It's going to be different for different people. Metformin works in the liver by making you sensitive to your own insulin. So it needs to build up in your system. I started off on 500 then within a few days went to 1000. It lowered it somewhat but not enough. I then went to 1700 mg and could get my bgs to about 120-130. Finally I had to go to 2550 and a very low carb diet (30 carbs a day) before I saw bgs below 100. But as I said maybe that was just me. The low carb diet really helped me the most. Metformin does not allow you to eat more carbs as some D drugs do.

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Old 10-29-2011, 20:59   #8
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I wanted to add that it wasn't until AFTER I started the LC/HF diet that I achieved normal and stable BGs. Despite the Metformin and Insulin, normal and stable was not possible without reducing my daily intake of carbs to roughly 30-50 grams. Insulin isn't supposed to be used so you can keep eating the same amount of carbs. My Doc purposely prescribed just enough to get me close to normal and then challenged me to go the rest of the way downward by making dietary changes. I like that approach and it's working well for me. I've been going very hypo (meaning below 70) lately before meals that I'm actually going to need to start reducing my Insulin. But, I plan to discuss that with my Doc next week during my 1 month check-up.

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Old 10-29-2011, 23:28   #9
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I like your doctors approach! Sounds like a keeper.

"Very hypo"? Sounds pretty normal to me.

Good luck and report what he says!

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Old 10-29-2011, 23:53   #10
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Quote:
Originally Posted by Patdart View Post
"Very hypo"? Sounds pretty normal to me.
Nope - not normal at all. 70 is the lowest end of "normal." I've been going into the mid 50's, thus "very hypo." Then, as I stated, your body will send out all kinds of "alarm bells" to alert you to get yourself restored to normal. In which case, I do not over-correct, I just pop a glucose tablet and re-test at 20 minute intervals until I am back up to normal.

Then, I assess the situation and ask myself things like, how many carbs had I eaten, how long ago, etc. For instance, one time I had eaten a Taco salad and a few bites of the shell and just 2 hours later I was at 56. My Doc currently has me injecting 20 units pre-meal if my BG is 150 or less (and more if it's higher). What this tells me is that 20 units of Insulin is now too MUCH for me, especially if I'm having a no carb or very low carb meal. So, I'll be discussing my ideas of how to "fine tune" things with my Doc next week so I can maintain my target he has set for me which is 70-130.

Hope this helps clarify things a little better

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