Rapid Acting Insulins: Side Affects

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Rapid Acting Insulins: Side Affects


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Old 02-26-2014, 22:56   #1
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Default Rapid Acting Insulins: Side Affects

What type of Rapid Acting Insulins are currently available to Type 1 Diabetics (UK)?

I seem to be very susceptible to the lil side affects of each and(I believe) Novorapid doesn't suit me in the slightest.

Has anyone else had side affects associated to Novorapid and/or switched to alternatives? Would love to here your stories. Amongst other things I have actually read that it can lower Potassium levels significantly. It also seems to make me massively hungry ... ?!?

Many Thanks

Dan

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Old 02-26-2014, 23:09   #2
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Welcome to the Forum, VL!

You'll find lots of support, info and the best kind of nosiness here.

I'm not in the U.K., but I'd like to get straight into the nosiness, and ask you a few questions. If you could give us some more info, you might get better answers. So. Here goes:

-- What kinds of rapid insulins have you tried thus far?

-- Syringe/Needle, Pump, or Pen?

-- What kind(s) of symptoms are you experiencing from each brand?

-- How do you schedule and measure your insulin doses?

-- Are you on an eating plan? If so, please feel free to share details.

Here's hoping you find your answer(s)!

In the meantime ... please read a lot, post a lot and ... most of all ... please keep us posted!

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Old 02-26-2014, 23:49   #3
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I have tried all the major rapid acting insulin available in the US. That includes Humalog, Novolog, Apidra and Regular insulin. I have not had any side effects from any of them. I can say they all react a bit differently as far as strength and duration. What kind of side effects are you experiencing?

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Old 02-27-2014, 01:02   #4
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The being hungry could be the blood glucose level have you checked that when you are hungry.

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Old 02-27-2014, 01:32   #5
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Hello. My son uses humalog and he's fine with it. I don't think the insulin makes you hungry, maybe you need to up the protein and fat in your diet to curb the hunger pangs. I didn't know that insulin injections affect your potassium levels. I now have to read up on that. Thanks for the info.

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Old 02-27-2014, 22:54   #6
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Ok. So the Symptoms I seem to get after taking Novorpaid (Novolog) are as follows:

- Sweaty and Flustered from about 1 hour after injection up to around 3 hours after
- incredible aches in both Arms and Leg muscles
- Brain Fog and loss of ability to concentrate
- Incredible Tiredness after injection - fall asleep a lot
- Itchiness over whole body

I have looked into my BS's around the time of injection and in the hours afterwards and there seems no discernible reason why I get these symptoms - either higher or low BS.

- After taking Lantus I get the common stinging pain at site. Then I get stinging pains going throughout my legs and ankles/feet. It only seems to come on immediately after taking injection.

Actually there are several more but these are the most typical.
-

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Old 02-27-2014, 23:37   #7
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That's crazy. I've honestly never heard of the pains going through anyone's body like that. The symptons are somewhat close to hyper, but I'd just make a Dr. appt and follow up with him/her.

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Old 02-28-2014, 00:30   #8
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Talk to your dr. Some people are allergic to different insulins. Ask if you can try a different rapid insulin. Also if you are having side effects with Lantus, try switching that too.

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Old 02-28-2014, 09:17   #9
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I'm in the States and so unsure of possible differences in the UK.

I use Humalog in my pump, having switched from Novolog around that time the result of my insurance company having changed their formulary.

Fortunately, I find Humalog much better as regards side effects. While not nearly so dramatic as yours, I do experience insulin side effects, primarily bloating in my hands and feet when the bolus is large (anything over about 2 units). The edema is generally accompanied by an increase in neuropathy pain as well. Too many carbs and too large a bolus also produces an odd sensation of the two "fighting" for dominance. Its unpleasant.

Humalog also seems more predictable in its action.

In large part, I used far more insulin while on MDIs that I think contributed to the problem. A combination of pumping and quite strict control over carb intake has helped significantly. Hunger also seems associated with excess (or too little) insulin for me.

Its impossible to refine boluses if you're using pens as you cannot take partial units. With a needle you can, but a bolus of less than 1 unit requires mixing with saline solution that may not be so easy or readily available.

My pump allows for half-unit increments and calculates boluses allowing for any remaining insulin on board. Its likely not precisely accurate, but still better than my own calculations.

I may be wrong, but my recollection is that Novolog is a completely synthetic product while Humalog is not. It could well be that we experience these Novolog side effects as a result. Worth checking with your doc in case its an allergic reaction in any event.

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Old 02-28-2014, 15:00   #10
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Quote:
Originally Posted by Tamagno View Post
I'm in the States and so unsure of possible differences in the UK. I use Humalog in my pump, having switched from Novolog around that time the result of my insurance company having changed their formulary. Fortunately, I find Humalog much better as regards side effects. While not nearly so dramatic as yours, I do experience insulin side effects, primarily bloating in my hands and feet when the bolus is large (anything over about 2 units). The edema is generally accompanied by an increase in neuropathy pain as well. Too many carbs and too large a bolus also produces an odd sensation of the two "fighting" for dominance. Its unpleasant. Humalog also seems more predictable in its action. In large part, I used far more insulin while on MDIs that I think contributed to the problem. A combination of pumping and quite strict control over carb intake has helped significantly. Hunger also seems associated with excess (or too little) insulin for me. Its impossible to refine boluses if you're using pens as you cannot take partial units. With a needle you can, but a bolus of less than 1 unit requires mixing with saline solution that may not be so easy or readily available. My pump allows for half-unit increments and calculates boluses allowing for any remaining insulin on board. Its likely not precisely accurate, but still better than my own calculations. I may be wrong, but my recollection is that Novolog is a completely synthetic product while Humalog is not. It could well be that we experience these Novolog side effects as a result. Worth checking with your doc in case its an allergic reaction in any event.
Just an FYI, I use syringes with half unit increments, which means you can actually get fairy accurate up to the quarter unit. You can even get pens with half unit increments.

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