Links Between Nutrients, Genes and Cancer Spread Documented

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Links Between Nutrients, Genes and Cancer Spread Documented


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Old 08-29-2012, 13:15   #1
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Default Links Between Nutrients, Genes and Cancer Spread Documented

Links between nutrients, genes and cancer spread documented

ScienceDaily (Aug. 27, 2012) More than 40 plant-based compounds can turn on genes that slow the spread of cancer, according to a first-of-its-kind study by a Washington State University researcher.

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"People for the most part did not set out in their research goals to study metastasis suppressor genes," says Meadows. "It was just a gene that was among many other genes that they had looked at in their study."

But Meadows took the studies and looked to see when metastasis suppressor genes were on or off, even if original authors didn't make the connection. In the end, he documented dozens of substances affecting the metastasis suppressor genes of numerous cancers.

He saw substances like amino acids, vitamin D, ethanol, ginseng extract, the tomato carotenoid lycopene, the turmeric component curcumin, pomegranate juice, fish oil and others affecting gene expression in breast, colorectal, prostate, skin, lung and other cancers.

Typically, the substances acted epigenetically, which is to say they turned metastasis suppressor genes on or off.

"So these epigenetic mechanisms are influenced by what you eat," he says. "That may also be related to how the metastasis suppressor genes are being regulated. That's a very new area of research that has largely not been very well explored in terms of diet and nutrition."

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Old 08-29-2012, 14:03   #2
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Hmm, do I detect an odor of bias or "agenda" here? Why does the title mention "plant" sources and then partway down the article refers to "natural" sources which by then the reader has been guided to associate with "plants".

But, the list is a mixed bag. Vitamin D is on the short list mentioned in the summary. Just glancing at the top 12 best food sources of Vitamin D, they are ALL animal sources. Another one is amino acids. These come from both plant and animal but are most available (and complete) from animal as opposed to plant sources.

Fish oil is also pretty hard to get from plants.

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Old 08-29-2012, 17:10   #3
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The citation is a review article from a small journal. The take home message is rather obvious IMO, and simplistic. We've been mapping the methylome and other epigenetic marks for some time, it's an active area of research with more questions than answers and the link provided doesn't really contribute anything.

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