Some omega-3 oils better than others for protection against liver disease

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Some omega-3 oils better than others for protection against liver disease


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Old 02-06-2013, 11:15   #1
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Default Some omega-3 oils better than others for protection against liver disease

Some omega-3 oils better than others for protection against liver disease | News & Research Communications | Oregon State University

CORVALLIS, Ore. – Research at Oregon State University has found that one particular omega-3 fatty acid has a powerful effect in preventing liver inflammation and fibrosis – common problems that are steadily rising along with the number of Americans who are overweight.

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“Omega-3 fatty acids are typically recommended for the prevention of cardiovascular disease,” Jump said. “Recommended intake levels of omega-3 fatty acids in humans for disease prevention are around 200-500 milligrams of combined DHA and EPA per day.”

Levels used in therapy to lower blood triglycerides, also a risk factor for cardiovascular disease, are higher, about 2-4 grams of combined EPA and DHA per day. The OSU studies with mice used DHA at levels comparable to the triglyceride therapies.

“DHA was more effective than EPA at attenuating inflammation, oxidative stress, fibrosis and hepatic damage,” the researchers wrote in their conclusion. “Based on these results, DHA may be a more attractive dietary supplement than EPA for the prevention and potential treatment of NASH in obese humans.”

This work was the result of a four-year study supported by the USDA National Institute of Food and Agriculture, as well as the National Institutes of Health. Co-authors on the paper included Christopher M. Depner and Kenneth A. Philbrick, both graduate students in the Nutrition Graduate Program at OSU.

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