Adult Stem Cells Could Hold Key to Creating Cure for Type 1 Diabetes

Go Back   The Diabetes Forum Support Community For Diabetics Online > Diabetes Forum Start Here > Diabetes News

Diabetes News The Diabetes News section is a place to share any new stories or information you have come across related to Diabetes for the rest of the forum to share and discuss. If you have seen or read about new medication, diabetes treatments, medical breakthroughs or any interesting stories of personal interest then please post and discuss them here. From time to time we will take some of the Diabetes News stories from this section and write them up in our Diabetes Blog.


Adult Stem Cells Could Hold Key to Creating Cure for Type 1 Diabetes


Closed Thread
 
Shared Thread Thread Tools
Old 05-30-2013, 11:01   #1
Senior Member
 
Join Date: Jun 2012
Location: USA
Posts: 1,288

Member Type
Type Pre
Diagnosed in 2005

1124 likes received
692 likes given
Default Adult Stem Cells Could Hold Key to Creating Cure for Type 1 Diabetes

Adult Stem Cells Could Hold Key to Creating Cure for Type 1 Diabetes - Institute for Clinical and Translational Science (ICATS)

Combining bone marrow cells with new drug restores insulin production

Millions of people with type 1 diabetes depend on daily insulin injections to survive. They would die without the shots because their immune system attacks the very insulin-producing cells it was designed to protect. Now, a University of Missouri scientist has discovered that this attack causes more damage than scientists realized. The revelation is leading to a potential cure that combines adult stem cells with a promising new drug.

(snip)

"The combination of Ig-GAD2 and bone marrow cells did result in production of new beta cells, but not in the way we expected," Zaghouani said. "We thought the bone marrow cells would evolve directly into beta cells. Instead, the bone marrow cells led to growth of new blood vessels, and it was the blood vessels that facilitated reproduction of new beta cells. In other words, we discovered that to cure type 1 diabetes, we need to repair the blood vessels that allow the subject's beta cells to grow and distribute insulin throughout the body." Zaghouani is pursuing a patent for his promising treatment and hopes to translate his discovery from use in mice to humans. He is continuing his research with funding from the National Institutes of Health and MU.

The discovery is reported in the current online issue of Diabetes, the American Diabetes Association's flagship research publication. Habib Zaghouani, PhD, J. Lavenia Edwards Chair in Pediatrics, leads the research with his team at the MU School of Medicine.

"We discovered that type 1 diabetes destroys not only insulin-producing cells but also blood vessels that support them," Zaghouani said. "When we realized how important the blood vessels were to insulin production, we developed a cure that combines a drug we created with adult stem cells from bone marrow. The drug stops the immune system attack, and the stem cells generate new blood vessels that help insulin-producing cells to multiply and thrive."

kantim is offline  
Closed Thread

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are On
Pingbacks are On
Refbacks are Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
Cardio could hold key to cancer cure kantim Diabetes Forum Lounge 1 04-27-2013 18:18
Researchers find that vitamin D may reduce the risk of adult type 1 onset diabetes Editor Diabetes News 0 02-08-2013 09:50
Joslin scientists report the first generation of human induced pluripotent stem cells kantim Diabetes News 0 02-02-2013 10:52
Diabetes distresses bone marrow stem cells by damaging their microenvironment kantim Diabetes News 1 02-01-2013 18:32
Embryonics stem cells and diabetes MariaJ Diabetes News 0 01-11-2013 13:05

LEGAL NOTICE
By using this Website, you agree to abide by our Terms and Conditions (the "Terms"). This notice does not replace our Terms, which you must read in full as they contain important information. You must not post any defamatory, unlawful or undesirable content, or any content copied from a third party, on the Website. You must not copy material from the Website except in accordance with the Terms. This Website gives users an opportunity to share information only and is not intended to contain any advice which you should rely upon. It does not replace the need to take professional or other advice. We have no liability to you or any other person in respect of any content on this Website.


All times are GMT +1. The time now is 05:44.




Powered by vBulletin®
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
Search Engine Optimization by vBSEO
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.
User Alert System provided by Advanced User Tagging v3.1.0 (Pro) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.