Could Turning On a Gene Prevent Diabetes?

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Could Turning On a Gene Prevent Diabetes?

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Old 07-23-2013, 11:45   #1
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Default Could Turning On a Gene Prevent Diabetes?

Could turning on a gene prevent diabetes? - UdeMNouvelles

Type 2 diabetes accounts for 90 % of cases of diabetes around the world, afflicting 2.5 million Canadians and costing over 15 billion dollars a year in Canada. It is a severe health condition which makes body cells incapable of taking up and using sugar. Dr. Alexey Pshezhetsky of the Sainte-Justine University Hospital Research Center, affiliated with the University of Montreal, has discovered that the resistance to insulin seen in type 2 diabetics is caused partly by the lack of a protein that has not previously been associated with diabetes. This breakthrough could potentially help to prevent diabetes.
“We discovered that Neu1, a protein nicknamed after “neuraminidase 1”, turns the absorption of sugar “on” or “off” in body cells, by regulating the amount of sialic acid on the surface of cells”, Dr. Pshezhetsky explains.

“We are now trying to find a way to restore Neu1 levels and function in diabetes. If we can remove sialic acid residues from the cell surface, this will force the insulin receptor do its job of absorbing blood sugar properly. This could give doctors an opportunity to reduce the use of insulin therapy, and might help to reduce the diabetes epidemic, says Dr. Pshezhetsky.

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Old 07-25-2013, 03:28   #2
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Wouldn't that be a fascinating discovery!

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Old 07-25-2013, 06:04   #3
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Yes, and I wish that this procedure be tested, approved as early as possible so patients like me can immensely benefit.

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