New Type of Protein Modification that May Play a Role in Cancer and Diabetes

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New Type of Protein Modification that May Play a Role in Cancer and Diabetes


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Old 08-02-2013, 12:18   #1
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Default New Type of Protein Modification that May Play a Role in Cancer and Diabetes

Scripps Research Institute Scientists Discover a New Type of Protein Modification that May Play a Role in Cancer and Diabetes

LA JOLLA, CA – August 1, 2013 – Scientists at The Scripps Research Institute (TSRI) have discovered a new type of chemical modification that affects numerous proteins within mammalian cells. The modification appears to work as a regulator of important cellular processes including the metabolism of glucose. Further study of this modification could provide insights into the causes of diabetes, cancer and other disorders.

“It appears to be an intrinsic feedback mechanism in glucose metabolism, but I suspect that its other functions throughout the cell will prove at least as interesting when they are more fully elucidated,” said Benjamin F. Cravatt, chair of the Department of Chemical Physiology and member of the Skaggs Institute for Chemical Physiology at TSRI.

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Old 08-03-2013, 08:54   #2
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First it was the MG, now this 1,3-BPG. Glucose metabolism & it's glucotoxicty.
Where's my steak ?

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