How diabetes drugs may work against cancer

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How diabetes drugs may work against cancer


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Old 03-18-2014, 13:36   #1
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Default How diabetes drugs may work against cancer

A major mitochondrial pathway that imbues cancer cells with the ability to survive in low-glucose environments has been pinpointed by researchers. By identifying cancer cells with defects in this pathway or with impaired glucose utilization, the scientists can predict which tumors will be sensitive to these anti-diabetic drugs known to inhibit this pathway.


How diabetes drugs may work against cancer - Technology Org

For several years, a class of anti-diabetic drugs known as biguanides, has been associated with anti-cancer properties. A number of retrospective studies have shown that the widely used diabetes drug metformin can benefit some cancer patients. Despite this intriguing correlation, it has been unclear how metformin might exert its anti-cancer effects and, perhaps more importantly, in which patients.


http://www.nature.com/nature/journal...ture13110.html

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