metformin, aging

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metformin, aging


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Old 06-03-2014, 20:40   #1
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Default metformin, aging

From Science Digest, news about metformin & aging. Of course, it's just worms so we humans should assume this has zero relevance for us, a step forward in understanding how metformin works or anything else except about wormy physiology. Not sure why I'm posting the link, now that I think about it. Chalk it up to the silly retired (diabetic) scientist in me, I guess.

Anti-diabetic drug slows aging and lengthens lifespan, animal study suggests -- ScienceDaily

" Summary: Researchers have provided new evidence that metformin, the world’s most widely used anti-diabetic drug, slows aging and increases lifespan. Scientists teased out the mechanism behind metformin's age-slowing effects: the drug causes an increase in the number of toxic oxygen molecules released in the cell and this, surprisingly, increases cell robustness and longevity in the long term."
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6/28/2012: 500 mg metformin. labs: FBG = 212, A1c = 9.2. weight: 174
7/7/2012: started 2000 mg metformin XR & LC/HF diet
9/28/2012 labs: FBG = 144, A1c=7.5. weight = 160; 12/1/2012 MN 1-mo FBG 103, 2-hr post = 128 // weight = 152 lb
12/30/2012 FBG 1-mo MN =97; 2 hr post MN=121;
1/2/2013: A1c = 6.5 11/2013 A1C=6.6 weight = 147 lb
4/2014 A1C=6.5 weight = 150 lb. 12/2014 A1C=6.5 weight = 147 lb.

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Old 06-03-2014, 20:50   #2
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This wouldn't surprise me considering the other known benefits that it has.

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Old 06-04-2014, 07:28   #3
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After reading the article it occurred to me that Metformin and Viagra have some common properties.

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Old 06-04-2014, 13:45   #4
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Cost isn't one of them.

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Old 06-04-2014, 14:58   #5
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Quote:
Originally Posted by mbuster View Post
Cost isn't one of them.
Well perhaps these chemicals, Metformin, Viagra, should be judged like any other processing aid. As for example a wetting agent ,release agent, catalyst, anti oxidant , UV absorber or anti foam etc .

ie by their CPP = cost per performance ratio.

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Last edited by Philip; 06-04-2014 at 15:01.
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Old 08-12-2014, 00:23   #6
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Yeah, Metformin kills sex drive and viagra revives it.

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