metformin during night?

Go Back   The Diabetes Forum Support Community For Diabetics Online > Diabetes Forum Community > Diabetes Treatment

Diabetes Treatment As there is currently no cure for the chronic, Diabetes mellitus – the emphasis must be on treatment and management to avoid complications. Please use this section to discuss how you carefully control and manage your Diabetes. Please let us know what is and isn’t working for you. Feel free to discuss all areas of treatment and management of Diabetes including diet, exercise, weight loss, insulin usage, oral drugs and more.


Like Tree5Likes

metformin during night?


Closed Thread
 
Shared Thread Thread Tools
Old 05-26-2014, 17:05   #1
Senior Member
 
Join Date: Nov 2013
Location: canada
Posts: 538

Member Type
Type 2
Diagnosed in 2013

140 likes received
405 likes given
Default metformin during night?

i'm currently having to take metformin
1000mg twice a day with meals
i'm having reasonable control except overnight
when I have to urinate hourly
I was wondering if it was safe to take 500 mg
somewhere in the night and see if I don't have to
urinate so much
if the dose will lower my levels any
has anyone tried this?

__________________

View pctm's full Diabetes Forum profile here.
pctm is offline  
Old 05-26-2014, 19:03   #2
Moderator
 
VeeJay's Avatar
 
Join Date: Jan 2012
Location: Midwest USA
Posts: 9,366

Member Type
Type 2
Diagnosed in 2010

11940 likes received
4403 likes given
Default

No one has answered yet so I'll give it a try.

Metformin, no matter when it's taken, is only built up in the bloodstream. It does not have immediate effect on BG like other drugs or insulin. It doesn't work that way. It works in the liver to reduce the amount of glycogen it stores, thereby, reducing the amount of glucose it is able to secrete back into the blood stream at a later time.

Quote:
'm having reasonable control except overnight
when I have to urinate hourly
I was wondering if it was safe to take 500 mg
somewhere in the night and see if I don't have to
urinate so much
You mention urinating at night. Is this because your blood sugar is high - say, above 200 most of the time? Well, this would cause urinating. But metformin would have absolutely no effect on this issue because, as I wrote above, it does not work like insulin to immediately (or even in an hour or two) lower blood sugar. If you BG is high, then your first priority is to get it lowered to below 140. The frequent urination will subside.

To address your statement of not have as good control overnight. As far as blood sugar levels go, it is natural for your BG to rise in the early hours of the morning. It is the way your body goes about waking you up. And it is the liver that provides the glucose to raise your BG. This is called dawn phenomenon (DP). Since we diabetics don't have an accompanying insulin response, BG continues to rise.

Metformin does help with DP. But if you are having high morning numbers, then it may be because you ate too many carbs the evening before.

DP is discussed at length on this forum. If you do a search for "dawn phenomenon" you'll find many recent and past threads on this subject.

Shanny and Tarek like this.
__________________
My low-carb recipe collection on Pinterest
https://www.pinterest.com/VRStudio1/...light-recipes/
70 yrs. Dx May 2010
Diet controlled: VLC/HF
BG steady with no highs or lows.
A1C in the 5% range.
____________________________________
Gluten intolerant, sensitive to dairy & eggs.
Eat no grains

Last edited by VeeJay; 05-26-2014 at 19:08.
VeeJay is online now  
Old 05-26-2014, 19:33   #3
Inactive Member
 
David Burke's Avatar
 
Join Date: Dec 2011
Posts: 5,318

Member Type
Type Undiagnosed
Diagnosed in None

5321 likes received
Default

Sorry, I don't take met so I can't answer questions that specific.

Sent from my iPhone

David Burke is offline  
 
Old 05-26-2014, 19:42   #4
Senior Member
 
Join Date: Mar 2010
Location: MA, USA
Posts: 1,489

Member Type
Type 2
Diagnosed in 1986

903 likes received
941 likes given
Default

What BG is reasonable control? As said met does not work like aspirin, it takes a while to build up.

__________________
I am not a doctor this is what works for me
You results may differ
diabetes86 is offline  
Old 05-26-2014, 19:53   #5
Senior Member
 
Mary,'s Avatar
 
Join Date: Mar 2013
Location: USA
Posts: 6,071

Member Type
Type 2
Diagnosed in 2013

5574 likes received
5676 likes given
Default

I've always urinated more since taking metformin. I've been on it for over a year at the full dose. I noticed the increase in urination within a few days after I started it even though it hadn't even built up yet in my body. I also notice that the closer I take it towards bedtime, the more I urinate during the night. Even though I take my full dose with dinner, it still causes increased urination even with good blood sugar control. I was taking it right before bed for a while to help with DP and it made it worse.

Sorry - I don't have a good answer for you since I haven't found one myself! I pretty much just put up with the increased output since taking met. It gives me really good blood sugar control so I just deal with the frequent bathroom trips during both day and night.

__________________

View Mary0110's full Diabetes Forum profile here.

Last edited by Mary,; 05-26-2014 at 19:56.
Mary, is offline  
Old 05-26-2014, 21:28   #6
Senior Member
 
silvertiger's Avatar
 
Join Date: Nov 2011
Location: Saskatchewan, Canada
Posts: 3,861

Member Type
Type Pre
Diagnosed in 2011

4282 likes received
5061 likes given
Default

As far as I know, Metformin shouldn't cause increased urination. High blood sugar or urinary infections can though. I've found that my frequency has decreased since the combo of Met and eating LCHF.

Shanny and foxl like this.
__________________

View silvertiger's full Diabetes Forum profile here.
silvertiger is offline  
Old 05-26-2014, 21:33   #7
Senior Member
 
Mary,'s Avatar
 
Join Date: Mar 2013
Location: USA
Posts: 6,071

Member Type
Type 2
Diagnosed in 2013

5574 likes received
5676 likes given
Default

If this helps you at all, Monday, here is the advice that Jenny gave regarding the same issue. I looked it up on her site when I first started experiencing the same problem, way back when.

"If you have trouble sleeping at night because you frequently have to get up to pee, it might be better to take your metformin before 3 PM because metformin may increase your need to pee at night. This is probably because the kidneys help remove it from the body and work harder in the 8 hours after you take the dose."

(Quoted from here.)

I've never actually tried this because I take my dose with dinner, but it may be worth a shot.

__________________

View Mary0110's full Diabetes Forum profile here.
Mary, is offline  
Old 06-02-2014, 17:54   #8
Active Member
 
Join Date: May 2014
Location: Fort Lauderdale, Florida, USA
Posts: 59

Member Type
Type 2
Diagnosed in 2012

56 likes received
17 likes given
Default Other causes....

There are 2 other possibilities I would add - (1) are you taking any blood pressure lowering meds? Many of the BP meds have a diuretic in them (I know mine does: Exforge), so if you started taking a new BP med - or anything with a diuretic in it - around the same time as the Metformin, then that could be the cause... and (2) have you made any changes to how much water you drink per day?

The Metformin instructions that I received from my pharmacy listed drinking a full glass of water with it - and in addition I have added more water - going for a full liter per day (or 4 full 16 once glasses) due to wanting to treat my kidneys nice (on advice from many resources I have read on the net - and due to some mild kidney pain while sleeping I had for a short time 8 months ago, which went away after increasing my water intake).


Tarek likes this.
TommyTechnology is offline  
Old 06-02-2014, 19:59   #9
Senior Member
 
Join Date: Jul 2010
Location: Missouri, USA
Posts: 837

Member Type
Type 2
Diagnosed in 1986

834 likes received
1807 likes given
Default

I combined Mary,'s advice (metformin at about 3 p.m.) with TommyTechnology's advice (more water) and it works well. Only two trips a night. Oh, and I take my dieretic in the morning.

__________________
A1c 12/30/12 6.0
A1c 6/24/13 5.5 !!
A1c 6/18/15 6.0
A1C 2/25/16 5.8

Meds: Metformin 1000mm/2 times a day
71 years old
Other meds: synthroid (no thyroid due to cancer); verapamil, losartan, water pill, standard eye drops for glaucoma.
JT Reagan is offline  
Old 06-10-2014, 11:04   #10
Active Member
 
Join Date: Apr 2014
Location: EGYPT
Posts: 51

Member Type
Type 2
Diagnosed in 2014

33 likes received
87 likes given
Default

Quote:
Originally Posted by TommyTechnology View Post
There are 2 other possibilities I would add - (1) are you taking any blood pressure lowering meds? Many of the BP meds have a diuretic in them (I know mine does: Exforge), so if you started taking a new BP med - or anything with a diuretic in it - around the same time as the Metformin, then that could be the cause... and (2) have you made any changes to how much water you drink per day?

The Metformin instructions that I received from my pharmacy listed drinking a full glass of water with it - and in addition I have added more water - going for a full liter per day (or 4 full 16 once glasses) due to wanting to treat my kidneys nice (on advice from many resources I have read on the net - and due to some mild kidney pain while sleeping I had for a short time 8 months ago, which went away after increasing my water intake).

I asked my doctor to change the Diuretics type of blood pressure lowering medications that I took only for 2 days because I couldn't handle it, to COZAAR (losartan potassium) which is Angiotensin II receptor blockers, and I could tolerate with it.

Tarek is offline  
Closed Thread

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are On
Pingbacks are On
Refbacks are Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
What is happening at night? Dodie37737 New Member Introductions 13 06-23-2013 22:45
Metformin and night sweats missriss68 Diabetes Treatment 6 05-23-2013 04:53
Hit 40 bs last night jsimms435 Diabetes 2 05-01-2013 17:32
I'm a night eater Kristina58 Diabetes Diet and Nutrition 21 11-30-2012 23:27
night sweats in 5 yr old lpete301 Diabetes Symptoms 9 08-13-2008 21:18

LEGAL NOTICE
By using this Website, you agree to abide by our Terms and Conditions (the "Terms"). This notice does not replace our Terms, which you must read in full as they contain important information. You must not post any defamatory, unlawful or undesirable content, or any content copied from a third party, on the Website. You must not copy material from the Website except in accordance with the Terms. This Website gives users an opportunity to share information only and is not intended to contain any advice which you should rely upon. It does not replace the need to take professional or other advice. We have no liability to you or any other person in respect of any content on this Website.


All times are GMT +1. The time now is 16:16.




Powered by vBulletin®
Copyright ©2000 - 2019, vBulletin Solutions, Inc.
Search Engine Optimization by vBSEO
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2019 DragonByte Technologies Ltd.
User Alert System provided by Advanced User Tagging v3.1.0 (Pro) - vBulletin Mods & Addons Copyright © 2019 DragonByte Technologies Ltd.