Diabetes 2 / HBV (glipizide?)

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Diabetes 2 / HBV (glipizide?)


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Old 06-16-2015, 16:57   #1
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Default Diabetes 2 / HBV (glipizide?)

Hi,

My wife has A1c 6.7 and is type 2 Diabetic.
She has a very minimal HBV blood virus count and is considered a "carrier."
The "new FDA approved" radiology scan is reading fatty liver at stage 2 (not very high.)

Our Dr. quickly prescribed glipIZIDE to help control her diabetes.
I opted out before buying, after reading what I could on glipIZIDE.

Later I found his reasoning is that "glipIZIde is not bad for the liver."
I question that remark.

Wife is trying to reduce carbs and control by diet with difficulty as the Gastro department told her it is ok to eat fruit and sugar, but not to eat carbs to help the fatty liver.
I know sugar is carbs, why argue the point.

My lean is against the Drs. judgment about glip and is toward Metformin ER if she will need to take diabetic medications.
Have to see Dr. again soon, after wife's next A1c test.


If anyone here has some info regarding this situation,and especially my choice of Metformin under these circumstance please give a response to me here.

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Old 06-16-2015, 17:09   #2
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The doctor probably is right in regards that it don't hurt liver, it hurts the pancreas, which also isn't good.

Metformin works with the liver to stop it from producing too much glucose, and it also help the cells receive the insulin. I think it's contraindicated in someone that has problem with the liver.

I am not a doctor though.

I would start with limiting carbs to a very low amt, possibly just green vegetable. Everything contains carbs except for protein and fat.

Other will come along and give the links we all use to Eat with OUr meters, and LCHF diet, at diet doctor.

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Old 06-16-2015, 18:21   #3
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Your instincts are correct, unclela. And Roxanne has said exactly what I'd have said - glipizide doesn't hurt the liver, but it will burn out her pancreas by constantly forcing it to produce insulin whether she needs it or not.

Better to have to inject insulin when you actually NEED it, than to take a pill which squeezes our already overworked pancreases to produce it. The problem is not that we need more insulin - what we need is metformin to open our cells' insulin receptors to allow the insulin that's already there to get in and nourish the cells; metformin is the ONLY drug which works for insulin resistance like this.

Here is the regimen I would advise for your wife:

Eat-to-your-meter
low-carb/high-fat way-of-eating

These methods have been proven over and over again to work safely and quickly, without doing more harm than good, which is what the sulfonylurea drugs (glipizide, et.al.) will do.




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Last edited by Shanny; 06-16-2015 at 18:23.
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Old 06-16-2015, 19:32   #4
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Thanks for replies, I am keeping up with it.

I've been encouraging the wife toward the LCHF Diet for 2 years now.
She is using the meter now.
The biggest problem is the Gastro Dr. telling her that she can eat fruit and sugar because it is not bad for her liver. In fact the primary care Dr. would agree that some cereal and fruit is just finem for a diabetic.
Because of that I was only able to get her A1C down to 6.7 from 6.8 in 4 months.
Now they will want her on meds for diabetes as to the probabilities involved because of the combination of other possible liver problems and diabetes dualistically working on the liver.

I will keep on trying to point the right direction out as I see it.

But if it comes to push and shove with the medical profession here and her
A1C is not improving enough to satisfy the situation I do have to know that metformin would be an acceptable alternative to glipIZIDE in her situation.

I might guess that the Dr. isn't sure either.

I read online yesterday that in 2012 experiments with laboratory animals showed metformin effective at 57% of the studies for reducing tumors and preventing liver cancers.

I would think metformin to be safe as studies also reveal that only 1% of the metformin users had any rise indicated on their blood panels for liver enzymes.

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Old 06-16-2015, 19:39   #5
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I have a history of Hep B, although I am one of the fortunate people who are not carriers, with no detectable virus. I too have Type 2 diabetes and fatty liver. I have been on metformin for some 13 years now, with no adverse effect on my liver. And I can not take Tylenol due to the effect on my liver! I use aspirin for the random headache. My doc runs a liver panel regularly, and my enzymes are always elevated, and while it fluctuates a lot the metformin has not changed anything.

I concur that your wife would be better off on Metformin than any glipzide. My own doc prefers to never use glipzides.

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Metformin 1000mg bid
Ranitidine 150 mg qd
Losartan 50 mg qd
Loratadine 10 mg qd
Pulmicort 180 mcg bid
Fluticasone 50 mcg qd
Ventolin 2 puffs prn
Tramodol 50 mg prn

A1C 6.6

Cinnamon, 1000 mg bid
Turmeric, 2000 mg qd
Vitamin D3 5000 mg qd
Fish oil 3000mg qd

Last edited by cathyy; 06-16-2015 at 19:47.
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Old 06-16-2015, 20:30   #6
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Could you point out to her that the doctors' methods are not working? How long does one have to follow their bad advice before one realizes it doesn't work, and will never work, no matter how long we use it? That's all I know to tell you . . . most of us have been there, done that, and the standard medical recommendations just don't work, regardless of how religiously we employ them.




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Old 06-16-2015, 23:01   #7
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Quote:
Originally Posted by cathyy View Post
I have a history of Hep B, although I am one of the fortunate people who are not carriers, with no detectable virus. I too have Type 2 diabetes and fatty liver. I have been on metformin for some 13 years now, with no adverse effect on my liver. And I can not take Tylenol due to the effect on my liver! I use aspirin for the random headache. My doc runs a liver panel regularly, and my enzymes are always elevated, and while it fluctuates a lot the metformin has not changed anything.

I concur that your wife would be better off on Metformin than any glipzide. My own doc prefers to never use glipzides.
Thanks for sharing your experience cathyy, it is helpful for me..!!

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Old 06-16-2015, 23:18   #8
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Quote:
Originally Posted by Shanny View Post
Could you point out to her that the doctors' methods are not working? How long does one have to follow their bad advice before one realizes it doesn't work, and will never work, no matter how long we use it? That's all I know to tell you . . . most of us have been there, done that, and the standard medical recommendations just don't work, regardless of how religiously we employ them.
Thanks Shanny !

I have been pointing everything out to her and she does fair with it..no more tortilla chips, rice, bread etc..

But like most of us her will for what she wants wins out. The doctor says fruit is ok so then she eats pounds of it.

My hands are full as she is also prone to any propaganda that says "fad foods" are good for diabetes and blood pressure. She has to have them in her mind. They never pan out for what they say they are to sell their products, as far as I know yet.
Right now it is Tahitian Noni and Chai Seeds every day.
It doesn't appear that her BGL's spike high after consuming them but I am sure they are not much benefit at all and $$$.

She gets on half track with testing with meter as ought to also.
And is difficult for me to move into a better direction for her.

Stubborn is the word.

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Old 06-16-2015, 23:29   #9
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Quote:
Originally Posted by unclela View Post
Thanks Shanny !

I have been pointing everything out to her and she does fair with it..no more tortilla chips, rice, bread etc..

But like most of us her will for what she wants wins out. The doctor says fruit is ok so then she eats pounds of it.

My hands are full as she is also prone to any propaganda that says "fad foods" are good for diabetes and blood pressure. She has to have them in her mind. They never pan out for what they say they are to sell their products, as far as I know yet.
Right now it is Tahitian Noni and Chai Seeds every day.
It doesn't appear that her BGL's spike high after consuming them but I am sure they are not much benefit at all and $$$.

She gets on half track with testing with meter as ought to also.
And is difficult for me to move into a better direction for her.

Stubborn is the word.
I have to stick my nose in here. It's not YOUR diabetes, it's HERS, and until she is ready to manage it, there is not much YOU are going to be able to do. She needs to control her diabetes herself.

Perhaps she can sign up to the forum herself and participate with us.

I know you love her, but being co dependent never helped anybody.

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Old 06-16-2015, 23:54   #10
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I was going to say something similar, Shanny. It really sounds like the Mrs. has still not truly accepted that she has diabetes and always will, and is looking for ways to avoid doing what must be done to avoid complications. The OP has the best of intentions, but he can not eat for her. She has to choose herself between the food she wants to eat and where uncontrolled diabetes inevitably ends up.

But I know how hard it is. My son has pre-diabetes and a dodgy gall bladder that needs to come out. He is deliberately eating high carb low fat to ease the gall bladder pain. I told him that the gall bladder issue can and should be treated surgically, and his dietary focus ought to be on LCHF - or as HF as one can go without a functioning gall bladder - to control the pre-diabetes. But I only told him once, as he is an adult and makes his own diet choices. While on vacation with him for a week, watching him eat pancakes for breakfast every day.

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Diagnosis: Type 2 2001?

Metformin 1000mg bid
Ranitidine 150 mg qd
Losartan 50 mg qd
Loratadine 10 mg qd
Pulmicort 180 mcg bid
Fluticasone 50 mcg qd
Ventolin 2 puffs prn
Tramodol 50 mg prn

A1C 6.6

Cinnamon, 1000 mg bid
Turmeric, 2000 mg qd
Vitamin D3 5000 mg qd
Fish oil 3000mg qd
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