Test Results ... well, THAT's annoying... - Page 3

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Test Results ... well, THAT's annoying... - Page 3


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Old 09-25-2012, 03:16   #21
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Quote:
Originally Posted by Adjitater View Post
I always thought a c-peptide should be done in conjunction with a GTT to asses how well they are producing insulin.
I have had an OGTT before. It was 14.7 (265) at 1 hr and 10.9 (196) at 2hr. It was a horrible drink, to boot. Nothing should ever be that sweet... Ick.

This is my 3rd C-Peptide and 1st GAD test. I get my A1c every 3 months.

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Dx'd T2 Dec 19, 2010 - Fasting BG: 14.8 (267), A1c: 12.1, Wt: 290lb (over 320lbs at my heaviest)

As of Apr 23, 2013: 14-day Avg Fasting BG: 4.7 (85), A1c (Dec21): 5.1%, Stats: 230lb, 6'3" now with 37" waist

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On Metformin only for meds. Exercise 6 days a week.
Supplement only with: Men's Multi-Vitamin, Vitamin D 2000iu/day, Aspirin 81mg, Cinnamon Extract and Fish Oil all 1x per day

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Old 09-25-2012, 03:32   #22
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Ok. But if they aren't doing your c-peptide ate the time they did the GTT then they don't know if you are producing enough or if you are just resistant to it. That is why I think it is important to do them together.

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Old 09-25-2012, 10:00   #23
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I wouldn't ask for those tests with an A1c of 5.7 or a spike of 30 points with a 12gm carb load. Also i wouldn't trust a c-peptide level on a low carb diet.

However, the doctors and you know what's best for you. Good Luck.

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Old 09-25-2012, 16:49   #24
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Hey Beefy...nice to see you are back! I've been trying to catch up as I've been absent here and there for health reasons (not necessarily my diabetes, just my craziness).

I recently had my C-Peptide retested since I was inquiring about going on pump therapy. When it was checked in 2009 it was on the high end of normal. This time it was at the very low end of normal. So I obviously assume that my beta cells are not functioning as well anymore. However, some here on the forum also pointed out that if you are eating a low carb diet, is it truly a correct reading as your pancreas would not need to produce as much? I am also on insulin, both basal and bolus, so would this reading still be correct? The whole reason the endo put me on insulin was to give my pancreas a rest. So are you really testing the production of the pancreas on its own, or from giving it a rest? It may still be resting! Maybe my pancreas is just lazy? When they checked my Gad-65 back in 2009 it was negative, so I knew that wasn't a factor at that time. However they did not recheck the Gad-65 this time; just the C-Peptide. I guess the Gad-65 doesn't matter for approval through insurance for pump therapy. I'm hoping that pump therapy will give me better control since I've gotten much better with using the insulin to keep my numbers lower, I still have times when I'm high and don't understand why. I would like to just have tighter control and keep my numbers under danger zones.

In any case, I hope this has given you something to consider. I would kill for numbers like yours. But, I also have other health issues going on that are hitting me rather hard right now, so this will also mess with my control.

I hope it all works out in the end. For all of us!

Really glad to see you back though. I get worried when I don't see people here that are usually here. It makes me worry that something happened to them. Guess that's one of the reasons I have anxiety issues...I worry too much

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Old 09-25-2012, 19:43   #25
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I am seeing my doc on Monday, first meeting since dx was given over the phone, up until now I have assumed I am type 2 because my numbers are under control with met and LCHF. I want to ask for several tests to get a clearer picture of what is broken. So C-Peptide definitely to see if I have LADA, what will the GAD-65 tell me since I am on LCHF and keeping my numbers down? I want to know if it is a resistance problem, a production problem, and signaling problem etc.

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Old 09-25-2012, 19:55   #26
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Quote:
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I am seeing my doc on Monday, first meeting since dx was given over the phone, up until now I have assumed I am type 2 because my numbers are under control with met and LCHF. I want to ask for several tests to get a clearer picture of what is broken. So C-Peptide definitely to see if I have LADA, what will the GAD-65 tell me since I am on LCHF and keeping my numbers down? I want to know if it is a resistance problem, a production problem, and signaling problem etc.
As far as I know, GAD antibodies do not correlate with carb intake, in any of the literature at least. I thought of that b/c I had one > 30 not long after dx, then a year later 3. But they might be different units ... anyhow I was not able to find a correlation in the literature!

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Old 09-25-2012, 20:09   #27
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Quote:
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Ok. But if they aren't doing your c-peptide ate the time they did the GTT then they don't know if you are producing enough or if you are just resistant to it. That is why I think it is important to do them together.
That's probably because my doctor is ... well, a nice family practitioner who doesn't know much about diabetic treatment...

I asked for the tests - that's why I got them. I didn't realize GTT and C-peptide are often done at the same time.

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Dx'd T2 Dec 19, 2010 - Fasting BG: 14.8 (267), A1c: 12.1, Wt: 290lb (over 320lbs at my heaviest)

As of Apr 23, 2013: 14-day Avg Fasting BG: 4.7 (85), A1c (Dec21): 5.1%, Stats: 230lb, 6'3" now with 37" waist

Low-Carb (Usually < 45-60g per day on a 3,000+ calories daily diet)

On Metformin only for meds. Exercise 6 days a week.
Supplement only with: Men's Multi-Vitamin, Vitamin D 2000iu/day, Aspirin 81mg, Cinnamon Extract and Fish Oil all 1x per day

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Old 09-25-2012, 20:16   #28
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Quote:
Originally Posted by beefy View Post
That's probably because my doctor is ... well, a nice family practitioner who doesn't know much about diabetic treatment...

I asked for the tests - that's why I got them. I didn't realize GTT and C-peptide are often done at the same time.
If you have a low demand for insulin, LCHF, lower IR by loosing weight, etc, your fasting C-Peptide will be low because you no longer need a lot of insulin to give you the same BG level.

It is sorta a one way test, if you have BG level in the normal to high range fasting and a high C-peptide, beyond normal, one would assume you have IR and are on your road to T2.

A thorough exam would be C-peptide FBG, then GTT test and pulling C-peptide with every BG reading, then correlating the two. Draw back here is if you have been on a LCHF diet your insulin production will be down any way and would skew the results.

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Old 09-25-2012, 20:25   #29
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Which is why when doing a GTT you're advised to stop LCHF for at least 3 days prior to test.

Sent from my iPhone

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Old 09-26-2012, 02:48   #30
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Which is why when doing a GTT you're advised to stop LCHF for at least 3 days prior to test.

Sent from my iPhone
I did ... sort of... I upped my carb intake to a minimum of 150g/day for 3 days prior. I couldn't bring myself to do more...

I learned that reading Steve Cooksey's site, Diabetes Warrior

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47 yr. old Male
Alberta, Canada

Dx'd T2 Dec 19, 2010 - Fasting BG: 14.8 (267), A1c: 12.1, Wt: 290lb (over 320lbs at my heaviest)

As of Apr 23, 2013: 14-day Avg Fasting BG: 4.7 (85), A1c (Dec21): 5.1%, Stats: 230lb, 6'3" now with 37" waist

Low-Carb (Usually < 45-60g per day on a 3,000+ calories daily diet)

On Metformin only for meds. Exercise 6 days a week.
Supplement only with: Men's Multi-Vitamin, Vitamin D 2000iu/day, Aspirin 81mg, Cinnamon Extract and Fish Oil all 1x per day

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