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Best anti-statin research links? - Page 2


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Old 12-19-2012, 18:45   #11
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Originally Posted by GretchenRS View Post
In this interview, they are discussing studies that showed "significant" increase in diabetes developing in statin drug patients. In particular the Women's Health Initiative study that showed a very high incidence of diabetes among post-menopausal women.
Very interesting considering the fact that I had been taking a statin drug for just over a year, then develope diabetes a few months ago. I am also in the post-menopausal group at age 55. My Dr. does not know that I quit taking the drug about a month ago. I guess she will find that out next month when I go in for my 3 month check.

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Old 12-19-2012, 19:20   #12
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I would think Dr. Golomb's article -- all 896 references in it -- should more than cover the issue.

I found it interesting how many times she referred to mitochondrial problems, specifically. AND the remark that muscle recovery is not always complete.

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Old 12-19-2012, 22:25   #13
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I was looking at the FDA's site, on why they changed the labels, and others. And what bothers me is that all them keep saying "the benefits far outweigh the risks", and they keep saying that the side effects only affect a small percentage, and this has been shown to be not true.
But the benefits? They have been shown for -- out of 100 men who suffered heart attacks, one less man on statin drugs will suffer a recurrence, than the men on placebos. And that is the only benefit.

The problem is that they view the cholesterol lowering effects of the drugs as "benefits". The whole thing is a fallacy. Especially because the very action of these drugs in preventing the body from making cholesterol, interferes with so many other essential to life and health functions.

Really I think the drugs should be banned altogether.

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Old 12-20-2012, 01:46   #14
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There are many studies which indicate that

a) statins do not work for prevention, they only marginally benefit 40 year old white men who have already had heart attacks

b) statins cause damage to many systems in the body: myopathy, arterial calcification, mitochondrial damage, increased risk of diabetes, liver damage, etc.

c) statins are not indicated for use in women, due to higher cholesterol being associated with lower mortality and because studies of statins in women do not show a reduction in mortality.

I second the suggestion to look at the references section of one of the good cholesterol books (the most recent is Bowden's Cholesterol Myth). From there you can identity studies that your doctor would care about. I understand that the book itself isn't something a doc would likely pay attention to...

Here are some studies that I am aware of that you may find helpful and are from "respectable" sources. There are more but this should help get you started. Whenever looking for studies, the best place to start is Google Scholar

Published in JAMA. It is a meta-analysis of 11 studies
Statins and All-Cause Mortality in High-Risk Primary Prevention
"This literature-based meta-analysis did not find evidence for the benefit of statin therapy on all-cause mortality in a high-risk primary prevention set-up."

Journal of Evaluation in Clinical Practice. 10 Year Trial
Is the use of cholesterol in mortality risk algorithms in clinical guidelines valid?
"Among women, cholesterol had an inverse association with all-cause mortality... clinical and public health recommendations regarding the 'dangers' of cholesterol should be revised. This is especially true for women, for whom moderately elevated cholesterol (by current standards) may prove to be not only harmless but even beneficial."

JAMA
Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women
"Statin medication use in postmenopausal women is associated with an increased risk for [Diabetes]"

Published in Atherosclerosis Journal
Statins use and coronary artery plaque composition
"Statin use is associated with an increased prevalence and extent of coronary plaques possessing calcium"

With all that said... what is most important is to understand the risks of statins, the populations where there are potential benefits and make a decision for yourself if you believe that they will help improve and extend your quality of life. Your doctor's support, while helpful, is not necessary to protecting your own health.

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Old 12-20-2012, 02:01   #15
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Thank you all! I've never used Google Scholar - so cool! I think I've got a good collection of stuff to send her now.

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Old 12-20-2012, 02:34   #16
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Thank you all! I've never used Google Scholar - so cool! I think I've got a good collection of stuff to send her now.
I've never looked into it myself, but the two that Daytona posted "Statins and All-Cause Mortality in High-Risk Primary Prevention" and
"Statins use and coronary artery plaque composition" are interesting and could cause your doc to pause. Most of the other links would likely bring about the "benefit exceeds risk" argument. Does your doc want the full article?

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Old 12-20-2012, 14:12   #17
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Thanks for those ... I am now armed. He will have arguments, but.

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Old 12-20-2012, 14:55   #18
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I know when I told my doctor that there is no relationship between cholesterol levels and heart disease, in fact 50 to 75% of people suffering heart attacks have low cholesterol levels, she was shocked and had never heard that. But to her credit, she took notes on what I said. And I also told her that statin drugs cause diabetes and neuropathy. I already have both, why should I take a drug that causes problems I already have?

Anyway she agreed to not put me on statins again.

Good luck Abra

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Total Cholesterol -- 185
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Old 12-20-2012, 21:18   #19
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OWC started cardiac rehab yesterday, and the therapist who evaluated him almost hurt herself in her rhapsodizing over the miracle statin drugs. Then I told her what his lipids were without statins and eating LCHF. I won't hassle her, but if she's dopey enough to reintroduced the subject with me, I'll definitely be honest with her.




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Old 12-20-2012, 22:11   #20
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My doc knows I'd never take them, she lets me manage my own care. I give up Metformin, she doesn't tell me to take it. I want a VAP done every time I get a lipid panel, she orders it. I want blood ketone strips prescribed, she does it, then asks me how I am using them. I think my A1c should be lower than 5.9, given all that I do, but she's ecstatic about it, given that I take no D meds.

What I want is for her to stop rote prescribing statins to other diabetics.

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