Odd GAD-65 Results

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Odd GAD-65 Results


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Old 05-31-2013, 18:32   #1
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Default Odd GAD-65 Results

Hi all,

I had my C-Peptide and GAD antibodies test last week and my C-Peptide was a 2.31 out of 3.4, meaning my pancreas is producing insulin on its own.

Today my primary called to say she got the results of the GAD test today and it is "slightly elevated". She told me that out of 5, "normal" - and she didn't define what that means - would be under 1. My score was a 1.2 and she said that is close to being a Type 1. I don't see how that could be?

Does she have that backwards? It seems to me that a much higher score would indicate Type 1. And if I'm producing insulin on my own, how could I possibly be close to being a Type 1?

Confused

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Old 05-31-2013, 18:38   #2
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So is she saying that you do have GAD antibodies, but just not very many of them? If you have any antibodies at all, that indicates type 1 or a sub-group of type 1 like LADA.

Yes, you can have antibodies and still be producing some insulin on your own. It means your pancreas isn't completely shot yet - that the antibodies haven't ruined it completely yet.




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Old 05-31-2013, 19:02   #3
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Quote:
Originally Posted by Shanny View Post
So is she saying that you do have GAD antibodies, but just not very many of them? If you have any antibodies at all, that indicates type 1 or a sub-group of type 1 like LADA.

Yes, you can have antibodies and still be producing some insulin on your own. It means your pancreas isn't completely shot yet - that the antibodies haven't ruined it completely yet.

So, is this like super-horrific news? My goal is to get off insulin altogether, and if I'm Type 1 then that dream is gone. She said herself that the results were confusing and mentioned something about an auto-immune problem. I do have a call in to the endo, but being Friday, I don't know when I'll be hearing back.

I'm getting really worried now. I have to go look up LADA.

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Old 05-31-2013, 19:13   #4
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Get the exact numbers from her just so you feel better.
I don't understand the comments on range either. I too thought either you had it or you didn't.

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Old 05-31-2013, 19:16   #5
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Get the exact numbers from her just so you feel better.
I don't understand the comments on range either. I too thought either you had it or you didn't.

Those are the exact numbers. The GAD test is 1.2 out of 5 and the C-Peptide test is 2.31 out of 3.4

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Old 05-31-2013, 19:30   #6
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Not sure what "out of 5" might mean, who was the lab?

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Old 05-31-2013, 19:37   #7
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Quote:
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Not sure what "out of 5" might mean, who was the lab?
Quest Diagostics

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Old 05-31-2013, 19:45   #8
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the reference range for c-pep at quest from my labwork is .8-3.1. so at 2.3 you are well in range and making insulin.
By exact numbers I meant what is the reference range for the antibodies. There is usually (not always) some range. I wasn't sure from your initial post if the range was 1-5 and you were 1.2. So you were in range--but is that the range for normal or what? Again I assumed the antibodies would be a got it or don't got it kinda test.
See if she can fax you copies of your results.

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Old 05-31-2013, 19:50   #9
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Quote:
Originally Posted by donnaB View Post
the reference range for c-pep at quest from my labwork is .8-3.1. so at 2.3 you are well in range and making insulin.
By exact numbers I meant what is the reference range for the antibodies. There is usually (not always) some range. I wasn't sure from your initial post if the range was 1-5 and you were 1.2. So you were in range--but is that the range for normal or what? Again I assumed the antibodies would be a got it or don't got it kinda test.
See if she can fax you copies of your results.
She told me the range is 1-5. Anything below 1 would be "normal", anything above the 1 is going to indicate antibodies, which means Type 1 or LADA. My score was a 1.2 - above the 1.

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Old 05-31-2013, 20:05   #10
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Ah, so this test says antibodies present.
I'd ask for a repeat test as it's borderline!

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