A question for the experts

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A question for the experts


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Old 05-29-2015, 19:35   #1
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Default A question for the experts

I could give a boring explanation as to where the question comes from, but here goes:

Same woman here

160 pounds. Same diet. Same meds. A1c 7.3

140 pounds. Same diet. Same meds. A1c 6.0 (6 months later)

As weight comes down, will the A1c follow?

Just to make it interesting, the only difference between the 2 readings was exercise.
NO exercise for the 2 months before that 6.0 reading.

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Old 05-29-2015, 19:44   #2
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Normally, yes. (but I'm not an "expert")

Why so mysterious?

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Old 05-29-2015, 20:01   #3
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We don't have the whole picture so we are playing guessing games.

Weight loss contributes to blood glucose control - agreed.

Sensible exercise contributes to blood glucose control - agreed

But, for example, anaemia (to pick on just one condition) will also produce a reduction in HbA1c and in this case that change doesn't reflect improvement in control.

So on the information provided, no expert will make the call. And there are NO experts on this forum. Just diabetics who have learned the hard way what works for them. If you want suggestions, please do not invite guessing games. Give the whole story and perhaps you will get a useful response.

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Old 05-29-2015, 20:36   #4
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Oh my goodness, I'm sorry I didn't post correctly. And sorry for referring to you as experts.

As I re-read my post (darn, no edit tool) the A1c was 6.8 to be compared to the 6.0.

Diagnosed in June 2014. A1c was 7.8.
~Placed on Metformin 500 mg twice a day. Diet, exercise and meds, taken seriously.

Tested in September 2014. A1c was down to 7.3.
~Very disappointed. Doc upped the Metformin to 1000 mg twice a day. It was this reading that made me question what was going on. I did some research and found from a credible source that exercise may inhibit the efficacy of Metformin. It was almost believable because I had altered my lifestyle so much to have the A1c come down by only 0.5 (in 3 months). Honestly, I figured diet alone would have done that.

Tested in Dec 2014. A1c was down to 6.8.~
Continued with closely controlled diet, exercise and same dose of Metformin. For 1 month. Then winter came and I decided to test my theory. I did not exercise at all for Jan and Feb, 2 out of 3 months.

Tested March 2015 A1c was down to 6.0.
~Weight down a total of 20 pounds since starting (6/2014). Doc was baffled about the exercise. I agreed with him that exercise is important and I of course started exercising again. I reminded him of the study and he just shook his head. But as I thought about it, if everything else is the same (meds, diet) I wondered if it was because I weighed less and not that I stopped exercising.

PS I'm not anemic.

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Old 05-29-2015, 20:42   #5
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Not an expert, but I do take metformin, have for 12 years, I exercise pretty much every day, I don't think exercise has any effect on metformin. Exercise along with meds AND LCHF will lower your BG, BP and weight. It works for me YMMV

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Old 05-29-2015, 22:10   #6
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I wish I had not used the term expert. It implied that I only wanted to hear from people who are experts. But in reality, it was a term of endearment, I think everyone on these boards are experts!

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Old 05-29-2015, 23:30   #7
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Umm OK I am an expert on diabetes, I know more about the care and management of diabetes than my MD or my diatition or my old Endo. If they are MDs then I certainly qualify as an expert as do MOST of you all on this board.

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Old 05-30-2015, 12:11   #8
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The body is a very complex organism and we hardly understand what goes on in there metabolically. Most of the studies that we read are statistical in nature & are prone to inbuilt defects because of that. There are a lot of variables in your own N=1 case study. Weight down 20 lbs, Metformin upped & exercise stopped for 2 months. One or all of them could have affected the outcome. A1c is also susceptible to fluctuations in Hemoglobin (possibly even Iron) concentrations, not necessarily anemia.

But a good job on lowering your A1c. Another 0.5 points will surely make you very happy.
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Old 05-30-2015, 16:21   #9
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Yes, I was very happy at the lowering of the A1c, but perplexed at the same time, as was the doc.

It will be interesting to see what it is this time with all 3 in play, diet, exercise and meds.

Thanks all, I appreciate it.

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