is there an alternative to metformin?

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is there an alternative to metformin?


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Old 02-05-2018, 23:53   #1
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Default is there an alternative to metformin?

tried and trusted preferred!
of late they are blaming it for my low B12.
thanks all

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Old 02-06-2018, 00:53   #2
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if you are type 2, I would say that a ketogenic diet could be an alternative. I dont have all your information to say definitive or not but if I was not at on a ketogenic diet , I would most likely be on metformin so I can say its my alternative

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https://www.dietdoctor.com/low-carb lists foods for LCHF

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Old 02-06-2018, 01:40   #3
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i have been on a low carb diet for years.
some older folks have the metformin B12 problem.
thanks

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Old 02-06-2018, 02:54   #4
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Originally Posted by anon125 View Post
i have been on a low carb diet for years.
some older folks have the metformin B12 problem.
thanks
could you define 'low carb'. this term means different things for different people.

I thought I have heard of a type of metformin that is used if someone cant stomach the regular metformin. I am not sure of the exact name but I will search

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Here are some good starting points to read

Blood Sugar 101 - VERY informative and accurate
http://www.diabetesforum.com/diabete...ng-method.html a tried and true testing method
https://www.dietdoctor.com/low-carb lists foods for LCHF

""You take the blue pill, the story ends. You wake up in your bed and believe whatever the doctors want you to believe. You take the red pill, you stay in Wonderland, and I show you how deep the rabbit hole goes." "
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Old 02-06-2018, 04:57   #5
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Take supplemental B12. Natural ways of getting B12 is mainly from eating animal products i.e. fish, poultry, dairy, eggs, meat, so if you can't/won't increase them you'll need to supplement.

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Old 02-06-2018, 13:20   #6
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Below is a link to article I found in Medscape last summer that gives reason as to why B12 is not absorbed well by diabetics using metformin over time.

https://www.medscape.com/viewarticle/719043

You may need to create a free account on medscape to view the article; below is what I cut and pasted from the article that gives some key highlights.

"The mechanism of vitamin B12 deficiency with metformin is undoubtedly due to malabsorption of vitamin B12 at its absorption site in the terminal ileum. Initially, it was believed that metformin caused proliferation of bacteria in the small bowel either due to an effect on intestinal motility or an increased intestinal glucose level.[8] However, the current and more likely explanation for metformin-induced vitamin B12 malabsorption and deficiency is that metformin has an effect on calcium-dependent membrane action in the terminal ileum.[9] Absorption of the vitamin B12-intrinsic factor complex is calcium dependent and metformin interferes with this absorption. In support of this hypothesis is evidence that dietary calcium supplementation reverses metformin-induced vitamin B12 malabsorption.[10] .....

In conclusion, vitamin B12 malabsorption is a chronic complication of metformin therapy which can present with irreversible neuronal damage. On metformin therapy vitamin B12 levels should be checked on an annual basis. An alternative and a more practical and cost-effective method to avoid vitamin B12 deficiency would be an annual vitamin B12 injection that would provide more than the annual vitamin B12 needs for every patient on chronic metformin therapy."

I brought this topic up with my physician in fall and he did not think that taking supplements or even getting B12 naturally from our diet would help due to metformin blocking it in our gut. B12 via injection would work. Fortunately, I not too low yet; on my B12 level; I am currently in the lower 1/3 of the normal range.

That being said we are now testing my B12 and folic each year. I was advised by my physician if you can get off metformin before your B12 is too low then your B12 levels will improve due to being able to be re-absorbed. But if it gets to low then you have no choice but get an annual B12 shots to supplement. I estimate if I am on metformin for a few more years then I will be too low. Going LCHF I will check my B12 levels in late summer of 2018 to see if I am absorbing from any from my diet since I now have a baseline to compare.

This conversation cemented the fact for me to go LCHF so that I can get off metformin for good.

Best,
fjk2013

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Last edited by fjk2013; 02-06-2018 at 13:26.
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Old 02-06-2018, 15:53   #7
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Low carb is no rice, wheat, sugar etc as per Jenny Ruhl
thanks


Last edited by VeeJay; 02-06-2018 at 18:58. Reason: fixed spelling errors
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Old 02-06-2018, 17:58   #8
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Iím confused . Can you expand on your diet please. Thanks

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Here are some good starting points to read

Blood Sugar 101 - VERY informative and accurate
http://www.diabetesforum.com/diabete...ng-method.html a tried and true testing method
https://www.dietdoctor.com/low-carb lists foods for LCHF

""You take the blue pill, the story ends. You wake up in your bed and believe whatever the doctors want you to believe. You take the red pill, you stay in Wonderland, and I show you how deep the rabbit hole goes." "
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Old 02-06-2018, 17:59   #9
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Quote:
Originally Posted by anon125 View Post
Low carb is now rice, wheat, sugar etc as per jenny rhul
thanks
I would not think those are low carb. When I said I follow LCHF; I really meant I follow a keto lifestyle; there is now way I would be where I am now if I ate any of those foods.

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Old 02-06-2018, 18:27   #10
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Quote:
Originally Posted by anon125 View Post
Low carb is now rice, wheat, sugar etc as per jenny rhul
I believe there are a couple of typos in anon's post. "now" should be "no" -- the Jenny "rhul" mentioned is Jenny Ruhl of BloodSugar 101.

So: no rice, wheat, sugar, etc. That (and root vegetables and maybe a few other categories) fits in with what most folks here understand as "low-carb" (though the daily amount is still up for question).

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