Vitamin D Deficiency Linked to Type 2 Diabetes Regardless of Weight

by Barbara Hewitt on February 25, 2015

A vitamin D deficiency is more closely linked to type 2 diabetes than being obese, according to a new study. It means that maintaining a healthy diet and being outdoors could help combat the risk of developing the condition.

People who have low levels of vitamin D are more likely to have diabetes regardless of how much they weigh, according to a new study from the Biomedical Institute at the Complejo hospital in Malaga, Spain, and the University of Malaga.

pillsIn a paper published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism, scientists say that the study clarifies the connection between vitamin D, obesity and diabetes.

Vitamin D helps the body absorb calcium and maintain bone and muscle health. The skin naturally produces this vitamin after exposure to sunlight. People also absorb smaller amounts of the vitamin through foods, such as milk fortified with vitamin D. More than a billion people worldwide are estimated to have deficient levels of vitamin D due to limited sunshine exposure.

‘The major strength of this study is that it compares vitamin D levels in people at a wide range of weights from lean to morbidly obese, while taking whether they had diabetes into account,’ said one of the study’s authors, Mercedes Clemente-Postigo.

The cross-sectional study compared vitamin D biomarkers in 118 participants at the university hospital Virgen de la Victoria in Malaga as well as 30 participants from the Hospital Universitari Dr. Josep Trueta in Girona, Spain.

All participants were classified by their body mass index (BMI) as well as whether they had diabetes, prediabetes or no glycaemic disorders. Researchers measured levels of vitamin D in the participants’ blood streams and vitamin D receptor gene expression in adipose tissue.

The analysis found that obese subjects who did not have glucose metabolism disorders had higher levels of vitamin D than diabetic subjects. Likewise, lean subjects with diabetes or another glucose metabolism disorder were more likely to have low levels of vitamin D. Vitamin D levels were directly correlated with glucose levels, but not with BMI.

‘Our findings indicate that vitamin D is associated more closely with glucose metabolism than obesity,’ another author Manuel Macías-González,

‘The study suggests that vitamin D deficiency and obesity interact synergistically to heighten the risk of diabetes and other metabolic disorders. The average person may be able to reduce their risk by maintaining a healthy diet and getting enough outdoor activity,’ he added.


The opinions expressed in this article do not necessarily reflect the views of the DiabetesForum.com Community and should not be interpreted as medical advice. Please see your doctor before making any changes to your diabetes management plan.

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