What do you all think to this: Medical Monday: Alzheimer's link to diabetes | todaysthv.com
Heh - a couple of years ago my alzheimer mom was worried about something and I told her not to, that she had taken care of it, she only had forgotten. She said, "That's right! I forgot I can't remember!"Sometimes I think I'm suffering from Alzheimer's but it doesn't take me long to forget about it...
It is not the high glucose which causes the problem but rather the "insulin resistance" of nerve cells in the brain which prevents it from taking up the glucose and using it for energy (i.e., ATP). It is NOT diabetes but rather a similar disorder in another system of the body. It is by no means the case that everyone who has this "diabetes of the brain" or "type 3 diabetes" (i.e., Alzheimer's) has regular diabetes. They are not directly related like that, although some correlation is suspected.I'm resurrecting this thread since I find no reference to it elsewhere. It seems that Alzheimers is effectively treated by inhaling insulin. The inhalation puts the insulin directly into the brain, where the high glucose seems to exacerbate memory loss. It works with both prevention and in slowing onset of alzheimers. Suzie Craft did this work and her study has integrity although she cautions it is early stage.
Medscape: Medscape Access
Salim? Could you provide links to the research being done by Dr. Veech? Google isn't helping me find anything.
The degeneration of those neurons and of similar brain cells in Alzheimer's disease has been linked to defects in the cells' energy-producing machinery, or mitochondria. In both diseases, mitochondria in some neurons are inefficient at metabolizing glucose. But the process by which mitochondria metabolize ketones isn't necessarily impaired in the two diseases.
Veech, Clarke, and four of their colleagues from Japan demonstrated 3 years ago that, in test tubes, the ketone D-beta-hydroxybutyrate protects neurons that have the mitochondrial defects associated with Parkinson's and Alzheimer's.
Salim: Your analysis of the brain glucose effects is accurate and my apologies for a hasty post that got it wrong. Insulin resistance of nerve cells is a likely mechanism.BTW, if you notice the paragraph about the "side effects" of the ketogenic diet which include rising triglycerides and LDL and falling HDL, it makes me wonder what on earth they did wrong.
My diet (and that of many others) is very close to the classical KD used to treat juvenile epilepsy, so how come we experience exactly the opposite on all counts? Drastically reduced triglycerides, big increase in HDL and a drop in LDL and blood pressure. (Not to mention favorable Type A LDL particle size.)
A ketone pill? Please! Just change your WOE. It is NOT a "horrible" diet when done right, its actually very pleasant and satisfying (but of course, many of you already know that!)
My suggestion as to how to lower your cholesterol (by which I assume you mean LDL):Salim: Your analysis of the brain glucose effects is accurate and my apologies for a hasty post that got it wrong. Insulin resistance of nerve cells is a likely mechanism.
I was inspired by your signature file and made this one in similar format. We are the same age and I can now post a one year result, almost to the day. Suggestions on how to lower LDL are welcome, but I am happy with the result so far. I estimate that I consume less carbs than you do, but that is my estimate not a direct measure. I also assume your 11 grandkids is a measure of stress reduction. My three teen-plus daughters are stress inducers so I expect your chemistry to be better than mine until these birds leave the nest. lol.