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Discussion Starter · #1 ·
Hello all and thank you for allowing me to participate in this forum.

I am a 42 year old, diagnosed with type 2 about 3 years ago. I currently weigh about 285 at around 20% body fat. I also have HTN (well controlled with meds) and Peripheral Artery Disease (PAD) of the legs. At one point in my life, I was a fairly accomplished weight lifter (525# squat, 455 Deadlift) but got away from it for 12 years and let my self go (hence, all the above noted complications). (Sorry if this seems like I am rambling).

Anyways, I currently am taking Glipizide (10mg) daily, Metformin (1000 mg daily) HCTZ and Lisinopril (For HTN) Pravastatin (Cholesterol) and Pletal as well as 325mg aspirin daily.

I am now in about my 40th hr of being a Non smoker which I am very pleased with (21mg nicotine transdermal patch at hr 27).

Anyways, I returned to weight lifting (4 day split, intense 1-1.5 hr sessions) in May of this year and doing some light cardio work 10-25 min 3-4x/wk (using a semi recumbant elliptical, tread mills etc make me cramp to quickly due to the PAD.) I also started back taking some supplements about a month ago (ZMA, Creatine, Protein Powder and a pre-workout supplement called Super Pump 250) and started seeing some nice gains. (Added 26lbs to my 1 rep estimated max on bench in 3 weeks) while maintaining 285 and loosing about 2-3% body fat checked by 3 site caliper testing. Lifting gives me a training mentality that I also generalize to my diet. I started using Calorie Count website, kept my intake about 2700, averaging about a 1500 caloric deficit daily. With this approach, I was able to get my weekly avg glucose to around 140. Not great, but a hell of a lot better as, I hate to admit, but prior to this, my diet was crap and I had pretty much stopped tracking my blood glucose levels (kind of a diabetic in denial/"F it" insanity took hold).

I know that may be a lot of calories for a diabetic, but I will burn about 4200-4500 on days I work out. I am a big boy even with out the belly ( I look sickly when below 215).

Anyways, here is my dilemma. Had an arteriograph on Friday, stint placed in Illian artery. Doctor said quit smoking or loose the feet. Done! Had to stop the Metformin due to the contrast die (risk of kidney damage). In the mean time, My PCP's office calls and says my creatinine level was way elevated, stop the metformin until I can see him. Since then, my best reading was 160 this AM (yes, I cheated a bit Saturday)
He also said quit the creatine, which is one of my favorite strength building supplements. According to him, even if the increase in creatinine is due to the creatine, in combination with the metformin, there is a risk for renal damage. I hope to get in to see him Tuesday. Any suggestions? I would like to get off the metformin as is seems it has many interaction dangers.
 

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Welcome aboard, agreutman . . . just never mind the rambling - we're nothing if not chatty around here! :D And kudos on quitting smoking . . . many of us are recovered smokers, and you'll do fine - I can see your mind is made up!

BTW, we're getting a large Ohio contingent - whazzup over there?! ;)

You do have a major juggling act to keep going. I'm going to quiet down & let the members with more knowledge about these things have the floor . . . just know that getting your blood sugar down and maintained will have a good effect on many other medical issues too.

Thank you for joining us and do visit often!

:welcome:
 

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Discussion Starter · #4 ·
Thanks for the reply Shanny. Not sure what is up with the Ohio peeps. If had to guess, I would say it is likely rooted in the strong germanic roots we have here. This is beer, band and Pennsylvania dutch cooking teritory :)
 

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Hello all and thank you for allowing me to participate in this forum.

I am a 42 year old, diagnosed with type 2 about 3 years ago. I currently weigh about 285 at around 20% body fat. I also have HTN (well controlled with meds) and Peripheral Artery Disease (PAD) of the legs. At one point in my life, I was a fairly accomplished weight lifter (525# squat, 455 Deadlift) but got away from it for 12 years and let my self go (hence, all the above noted complications). (Sorry if this seems like I am rambling).

Anyways, I currently am taking Glipizide (10mg) daily, Metformin (1000 mg daily) HCTZ and Lisinopril (For HTN) Pravastatin (Cholesterol) and Pletal as well as 325mg aspirin daily.

I am now in about my 40th hr of being a Non smoker which I am very pleased with (21mg nicotine transdermal patch at hr 27).

Anyways, I returned to weight lifting (4 day split, intense 1-1.5 hr sessions) in May of this year and doing some light cardio work 10-25 min 3-4x/wk (using a semi recumbant elliptical, tread mills etc make me cramp to quickly due to the PAD.) I also started back taking some supplements about a month ago (ZMA, Creatine, Protein Powder and a pre-workout supplement called Super Pump 250) and started seeing some nice gains. (Added 26lbs to my 1 rep estimated max on bench in 3 weeks) while maintaining 285 and loosing about 2-3% body fat checked by 3 site caliper testing. Lifting gives me a training mentality that I also generalize to my diet. I started using Calorie Count website, kept my intake about 2700, averaging about a 1500 caloric deficit daily. With this approach, I was able to get my weekly avg glucose to around 140. Not great, but a hell of a lot better as, I hate to admit, but prior to this, my diet was crap and I had pretty much stopped tracking my blood glucose levels (kind of a diabetic in denial/"F it" insanity took hold).

I know that may be a lot of calories for a diabetic, but I will burn about 4200-4500 on days I work out. I am a big boy even with out the belly ( I look sickly when below 215).

Anyways, here is my dilemma. Had an arteriograph on Friday, stint placed in Illian artery. Doctor said quit smoking or loose the feet. Done! Had to stop the Metformin due to the contrast die (risk of kidney damage). In the mean time, My PCP's office calls and says my creatinine level was way elevated, stop the metformin until I can see him. Since then, my best reading was 160 this AM (yes, I cheated a bit Saturday)
He also said quit the creatine, which is one of my favorite strength building supplements. According to him, even if the increase in creatinine is due to the creatine, in combination with the metformin, there is a risk for renal damage. I hope to get in to see him Tuesday. Any suggestions? I would like to get off the metformin as is seems it has many interaction dangers.
Welcome to the forum and hello from another Ohioan!
 

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Discussion Starter · #6 ·
Thanks for the welcome Breeze. Appointment set with my PCP Wed. Morning. Gonna talk to him about maybe switching to Actose from Metfromin. Also, my Type II onset was after I had a Cyst on my pancreas (They thought it was cancerous, thank God it was not). I wonder of this has anything to do with were this generated from. Is there a test to check Pancreatic Functon? (Besides blood enzyme levels)
 

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Thanks for the welcome Breeze. Appointment set with my PCP Wed. Morning. Gonna talk to him about maybe switching to Actose from Metfromin. Also, my Type II onset was after I had a Cyst on my pancreas (They thought it was cancerous, thank God it was not). I wonder of this has anything to do with were this generated from. Is there a test to check Pancreatic Functon? (Besides blood enzyme levels)
Why do you want Actos?

You can be tested for C-peptide, it is an indirect snapshot of insulin production.
 

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Discussion Starter · #8 ·
Why do you want Actos?

You can be tested for C-peptide, it is an indirect snapshot of insulin production.
From what I have gathered, both Actos and Metformin operate in very similar ways by increasing insulin sensitivity despite the fact that they are in 2 different classes. To be honest, I know nothing about it's side effects, which is why I am gonna talk to my Doc. It is not so much that I have a desire for Actos, it is more that I want to get an alternative to Metformin due to all the recent issues I have run into with bad interactions involving kidney damage etc.

Thanks for the tip on the C-peptide test and for your response.
 

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Thanks for the welcome Breeze. Appointment set with my PCP Wed. Morning. Gonna talk to him about maybe switching to Actose from Metfromin. Also, my Type II onset was after I had a Cyst on my pancreas (They thought it was cancerous, thank God it was not). I wonder of this has anything to do with were this generated from. Is there a test to check Pancreatic Functon? (Besides blood enzyme levels)
I wish you luck on your switch from Metformin to Actos. I was on Actos for a year and I was retaining alot of water and my doctor thought it was best to go off Actos. I don't miss it. It just wasn't a good drug for me.
 

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I just had to note that I am on so many of the same meds as you ... in my case ... 850 mg Metformin 2 X day, 10 mg Glipizide, Lisinpril, Lovastatin, etc.

Anyway, at the beginning of the year my primary Dr. put me on Actos and referred me to an endocrinologist at the prestigious Penn Rodebaugh Diabetes Center at the University of Pennsylvania Medical Center. It turned out my endocrinologist was the director of the center and considered a leading diabetes specialist. He immediately took me off the Actos. According to him it makes you gain weight! :yuck:
 

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Discussion Starter · #11 · (Edited)
Ok, saw the Doc today. Creatinine level was at 1.6 which is not too bad for some one with a lot of muscle mass and taking creatine. However, according to him, with the stress that metformin places on the kidneys, he is switching me to Genuvia (spelling?). Apparently, according to him, protocol is that anytime creatinine goes over 1.5, Metformin must be stopped ASAP. He too is not a fan of Actos. Also, he wants me to lay off of the creatine for another 2 weeks, come back and do another blood draw. If my levels drop, we will know it was just the extra creatine and I can resume taking it as long as I get plenty of water while on it.

Am very pleased with this. Thannks for the support and input all!
 

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Discussion Starter · #12 ·
Very pleased thus far. 2 days on Januvia and my readings have dropped from 160-180 to 120-135. Also, read on webmd.com that vinegar can help increase insulin sensitivity, so I have been puckering my face through 2 tbsp 2x/day. My PCP confirmed this. It seemed to help bring me out of the 200+range when I 1st had stopped the Metformin.
 

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Lately I haven't been taking any, but I always have a large bottle of apple cider vinegar in my kitchen. I'm beginning to think it doesn't do much if any good. I was taking 2 - 3 Tbsp, diluted in a glass of water, per day.
 
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