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Hey guys. My Dr put me on glimepiride today (2mg 1 time per day) and I am to take it with the Metformin (1000 2x per day). My question is, this can make me hypo, correct? How long after I take this medicine in the morning will it the to lower my BG level? I was told this was a fast acting drug so I just want to make sure I dont crash out when I take it. How fast does it actually act?

TIA!
 

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I was on the stuff less than one week due to hypos, but it was given to me with the expectation of hypos.

I later learned, it is an SU and can cause beta cell burnout. I too was told to take it twice per day. I took it in the am and halfway to lunch I hypo'd if I recall correctly.
 
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