Hi all, this is my first post. I have been a type 1 diabetic since 2002 and have been using either novolog and lantus or straight novolog with the pump since 2004. In the past my control has been tight and I have never had problems. Recently I have been fighting to keep my numbers under 300 and my Dr. does not seem to be taking me seriously. Here are the metrics, I was on .8 units/hr as a basal rate with my pump and 15:1 carb ratio. All of the sudden it seemed like novolog was not working. I called my Dr. and told him I though my pump was not working and asked if he could fill my old lantus and novo-pen prescriptions. I restarted paperwork for a new pump and started to do injections. This was not working so well so I increased the lantus from a Dr. recommended 20 to 30 units, that seemed to keep between meal time readings consistent however I was triple and quadruple shooting for boluses and novolog still is not keeping up. BTW all this is while I am still wearing the pump at .8/hr for a basal rate and doing manual injections of novolog. I read somewhere you can become immune to insulin so I got some humilin and take it as directed, 30-40 minutes before meal time ad really watch my carb intake at meals, it seems to help but does not seem to do all I need it to. I have tried multiple infusion sets and 2 different lot number and vials of novolog to make sure it was not a bad batch or infusion set. Last reading was 385, I ate 5 exchange units and took 15 units of humulin to no avail. I did not eat lunch and countered with 7 units of novolog (typical counter is 40mg/dl:1 unit novolog). Anyone have any thoughts? It seems like I have taken enough insulin to be swimming in it and it does nothing. PLEASE give me some input. I am healthy at this time and see no reason to be where I am at with the numbers.