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Hello all

I havent posted here in a long time, but my doctor has recently changed me from two Janumet pills (1000mg), one with breakfast and one with dinner, two pills at dinner. I also take Glicazide both in the morning and the evening. I am fining that my numbers are horrible, I was having good numbers before regularly between 4 and 6, and now I am ranging from 9 to 13. Is it normal for the body to have to take long for my body to adapt to the change in meds?

She also recommended I switch to Synjardy and Ozempic, do you think that would be a better option?

Just frustrated. Feel like crap now when I thought I was doing well!
 

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I wouldn't think that going from regular to time release version would have such a dramatic change with the chemistry already in your system. Did the change in BG happen quickly or slowly?

What are you eating, are you counting carbs? Me personally, I try to avoid most meds if at all possible. I guess I've read about too many potential bad side effects many of them have to offer.
 

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I might be misunderstanding the pill change, is the change just the timing and not the pill? Instead of 1 pill twice a day, its 2 pills once a day with dinner. If thats the case, I would think your fasting numbers would have went lower. Janumet is a class of drugs known as DPP-4 inhibitors. It is a mixture of Januvia and metformin. You can read about this and other classes of diabetes meds here

As far as the recommended drug change, Synjardy (a SGLT2 Inhibitor) is Jardiance with metformin, Ozempic (a GLP-1 Agonist) is semaglutide. See the above link. My opinion (that and a dollar will get you a cup of coffee at McDonalds) would be that the Insulin and Metformin would be the better option.

It could also be coincidental that the timing of the meds change aligns with the rise in BG. You might ask to be tested Type 1 antibodies. Type 1.5 (LADA) diabetes is often diagnosed as type 2 early on. If that is the case, then all these meds are useless and you should be taking insulin, which by the way, could also be effective and replace your current meds if you are in fact Type 2.
 
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