what happen, i had been taking onglyza with metformin and my neuoraphy pain had stopped. then i stopped taking onglyza around the first of july and about 45 days later my np returned in my last three toes of my left foot. my doctor started me on the kombiglyze xr 2 weeks ago and as of now it has'nt stop hurting.i also started 600 mg of alpha lipic and that has'nt work.....maybe its too soon to get relief. i take that the komiblyze xr 1000/5 is a combination of metformin and onglyza.So you were on saxagliptin (onglyza), and now you're taking saxagliptin + metformin? Many of us take metformin - what exactly is your question about it other than counting noses about who takes it?