Metformin: does it finally stop working for most people?

My metformin hasn't failed me yet, but I've been on it only 18 months. Pam has been on it for many years, if I'm not mistaken, and still trusts it.

I'm hoping that it will stop working for me soon. Why? Because I'm hoping to get off it altogether. I've been down from 2000mg to 1000mg per day for the last three months with hardly any difference in HbA1c - up only from 5.0% to 5.3%. I don't even know whether that slight change was due to the reduction in metformin or to something else.

I've got an appointment with my doctor next Monday to review the situation. I'm hoping that he'll agree to a further reduction or - better still - a trial period with no metformin at all.

Diet is the way to go for me!

Shanny said:

My metformin hasn't failed me yet, but I've been on it only 18 months. Pam has been on it for many years, if I'm not mistaken, and still trusts it.

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Yes actually, I have been taking it since sometime in the late 80's. At times I forget to take my evening dose when I really busy with work and school...if I go a few days with only taking half of my daily dose I can see the difference.

I've been taking Metformin since 2003 and last year I asked my doctor if I could stop it - just to see if stopping it made any difference in my blood sugar. The first two weeks without it didn't seem to make any difference...but..come the third week my blood sugars started to climb way beyond my target. By the 4th week I really noticed a difference. So I talked with my doctor again and we both decided that even though I thought it didn't make any positive contributions to my overall blood sugar targets, it was in fact helping out after all. I think Metformin's performance varies with each individual person.