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Discussion Starter · #1 ·
I have been taking 3x500mg Metformin for more than 10 years.
During all those years my diabetes has been under control A1c <6%.
In fact, when I started taking it it was more as precaution, to inhibit progress, rather than necessary.

In the last couple of years, however, I've suffered from acute dry mouth which has a negative effect on my teeth. It's a undiagnosable symptom which is exacerbated by the several meds I take. By elimination I determined that Mettfomin is the worst contributor--when I don't take my mouth is closer to normal.

So the question is there anything I could substitute for it, even if not by something as powerful, that could serve the same progress-inhibiting function.
 

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If you're determined to stop taking metformin, nothing I can say will prevent that. But I will say there is nothing else to replace it with. There are, of course, dozens of meds the pharmaceutical industry will tell you are safe, but metformin is the only one that doesn't do more harm than good.

If you care to share the other meds you take which you believe are not the cause of your dry mouth, I'd be interested in knowing what they are, and please include any OTC products. There are literally hundreds of things that cause dry mouth, but I haven't heard of metformin being one of those.
 

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Discussion Starter · #3 ·
Introduction

Inadvertently I posted without introducing myself first and it's not clear from the warning I received how exactly to correct that. I am assuming that I can add the introduction here.

I am a 67 yo white male living in San Francisco. I have been diagnosed with DM2 in 2000 and high cholesterol (HC), after having been diagnosed with high BP in 1998. I managed to bring DM2 &HC under control after a few months with lifestyle changes and a statin. BP was more difficult and it took 3 years to find a combination of meds and dosages that was effective. My diet is currently normal and I walk daily 20-60mins.

Currently: A1C=5.8-6.%; BP=130-135/75-85
 

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Hi, and thanks for responding.

Determined is too strong a word. I am just inquiring into whether there is an option. I am aware of the various DM2 meds and their pros and cons, but maybe others know things I don't or have some relevant experience.

My dry mouth may have a root cause that has remained undiagnosable by numerous specialists since 1997. The meds only contribute to it. I've taken all steps to minimize the symptoms (food, hydration, etc.) but they are insufficient and there are accompanying symptoms that have caused periodontitis and caries. I've checked the side effects of the dozen meds I've been taking for dry mouth side effect and eliminated about half without any problems. The ones left are no substitutable for various reasons (well researched).

Diltiazem 300mg
Telmisartan 80mg
Metformin 3x500mg
Potassium Citrate 15mEq
Atorvastatin 40mg
Aspirin 81mg

Since Metformin has not been critical for DM2 control, I stopped it for a few days and there has been significant improvement, since my question here.

If you care to share the other meds you take which you believe are not the cause of your dry mouth, I'd be interested in knowing what they are, and please include any OTC products. There are literally hundreds of things that cause dry mouth, but I haven't heard of metformin being one of those.
 

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Your dentist may be of assistance, they recommend various benign mouthwashes, etc for dry mouth. Next time you have a scaling appointment, I bet you'll get some help.
 

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is there anything I could substitute for it, even if not by something as powerful, that could serve the same progress-inhibiting function.
I don't think you're going to find another drug. But by making sure you don't eat more carbs than your body can safely metabolize will go a long way toward halting progression and avoiding diabetes complications.

You could probably do without the metformin as long as you monitor your BG carefully and make adjustments in your carb consumption if indicated. I am an advocate of increasing fats and lowering carbs until one is in dietary ketosis. This is the way I managing my diabetes. But if this weren't effective enough, then I'd not be adverse to using insulin. It's safe.
 

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Discussion Starter · #8 ·
Thanks.

Given an A1c <=6% for the last 15 years, despite the fact that my carb regimen is not strict, I've been taking Metformin mainly to inhibit progression. However, it may well be that it's been responsible for lack of progression, so dropping it may not be a good idea.

Re fats, I've also taken Lipitor for high cholesterol, so too liberal a fat regimen is not a good idea either. The med was reasonably effective in controlling lipids, but the risk of cognitive loss has been recently deemed significant for certain people and I have a appt with an endocrinologist to discuss this. If I drop the statin, it'll be hard to justify an increase in fats, particularly if my high cholesterol does not come from food, but is produced by my body.
 

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I know that before I was diagnosed a month and a half ago with Type 2, I had horrid dry mouth, and am on 2000mg a day of Metformin and my dry mouth has just about disappeared entirely. I agree with you that the dry mouth has had a horrid job on my teeth but hopefully things are on the way up in that respect. I have read that monitoring blood sugars are regular levels help bring your gums and teeth back under control which is what I am looking forward to. Going to the dentist 4 times a year, every 3 months, and being yelled at for bloody gums has not been fun. Especially when I brush, and floss, and use a waterpick, and mouthwash, it sucks. I hope that now that the drymouth is under control that I can get my gums in good shape and show the nasty hygienist that it was out of my control but not totally under control!

Good luck with you and your journey to good oral health.
 

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Tried mouthwashes. Did not solve the problem.
My wonderful volunteer hygienist told me while cleaning my teeth that I have sry mouth, negatively affecting my teeth. There are products made especially for this condition. I use biotene brand moisturizing mouth spray from Walgreens. He suggested a product from ocean, but I could not fond it. Product contains glycerin and seems to work well for me. YMMV
 

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I know that before I was diagnosed a month and a half ago with Type 2, I had horrid dry mouth, and am on 2000mg a day of Metformin and my dry mouth has just about disappeared entirely.
Now that you mention this I haven't woke up with a really dry mouth in quite a while. I use to wake up and my mouth was so dry a could hardly swallow. Years ago I blamed it on being a heavy beer drinker and figured it was the alcohol dehydrating me. But in the early 2000's I stopped the heavy drinking but my dry mouth didn't go away. My dental hygienist gave some solution you mix with water and shake it to activate it then swish it around but I never noticed it made any difference besides a really clean mouth.

Before being Dx with D I never drank water, the only water I got was in beer, coffee and pop. Since then I have be drinking 80 to 100 ounces of water a day. So lowing my BS and drinking all this water must of helped with the dry mouth.

Just another bonus to keeping BS under control:vs_smile:

oao - When I started taking Metformin and lisinopril doc told me I needed to drink a lot of water. Let us know if you get it figured out and what your doctor visit reveals.
 

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Oh, I know what you're talking about. I was diagnosed with Type 2 4 years ago, and since I started taking Metformin, my mouth is always dry (terrible feeling). Unfortunately, I didn't go to the doctor when I had the first symptoms, and it continued to progress until I lost 4 of my teeth. Anyways, my dietician forbade me to stop Metformin. So, I went to https://www.bridgedentalsmiles.co.uk/treatments/dental-implants/, got several implants for the missing teeth, and started a proper treatment for xerostomia. From that moment, I'm using saliva substitutes 8 times per day, and the feeling of dry mouth almost vanished. Surprisingly, dental implants have perfectly integrated, which means that this option is really working. Hope it will help you as well!
 
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