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Hi, I'm 52 years old and live in New Hampshire. I was diagnosed with type 2 diabetes in early 2016. I currently take Metformin XR. Last year in July I was diagnosed with a cholesterol granuloma benign cyst in my skull near my temporal lobe that required surgery. While I was in the hospital they put me on insulin instead of my metformin. I had been working very hard to try to get my bg under control, but it's been a nightmare since my surgery. I've been having some complications and was just released from being an inpatient with a suspected CSF leak. They couldn't find anything emergent, so they sent me home to monitor my symptoms. They had me on insulin again in the hospital and now I'm back on my metformin, but my bg readings are still all over the place. My PCP has been made aware of these crazy bg numbers and said things should stabilize. My question is how long does it take for my metformin to start working again? This may be the wrong place to ask this, but it's part of my introduction.

Premium Member
1,124 Posts
Welcome my friend... Pull up a seat and stick around. I am 100% sure that there are people here who will be able to narrow down your question and help you get the information you need. I do not take metformin so I can not intelligently answer your questions


I will ask that you start to get some information about diabetes and maybe attack it from a different point of view.

You say that you are working very hard to get your condition under control and I am 100% sure you are as per the doctors orders...

but what if there is a better way for you to try to get your condition under control....

Please watch this video and come back with any questions you might have.

If you remove carbs from your body for a length of time, you will more than likely find your BG go down on its own.

I went from 396BG to 75BG in 5 weeks without any medication. Look at the links in my signature, watch the video and let us know if you have any questions

I am sure there will be some folks come by to give you advice on the medformin

we are here to help, guide, advise or just listen if you need us

Super Moderator
10,015 Posts
Hi and welcome to the forum.

Sorry to hear of the problems you've experienced. As far as the cyst, did they have any idea of probable cause? The cysts are thought to be an inflammatory immune system response. Do you have chronically high cholesterol numbers?

The cyst, possibly being the result of an immune system response, could mean other things could be affected, thyroid function, pancreas function, etc. Has your doctor tested to see if you have antibodies that indicate your pancreas has lost its ability to produce sufficient insulin? There are like five different test that can be used to determine if you have actually may now be a type 1 instead of type 2?

The CSF leak could have resulted from the surgery. I have no experience with either the cyst or CSF, I just did a quick google search and read on each on a Cedars-Sinai and Mount Sinai hospital sites. Your doctors overseeing the treatment of the cyst should be the most able to have definitive information about anything related to it.

Are you having to take any medications as a result of the cyst or the CSF? Some medications can cause BG to go up. Are you taking meds for anything else? The metformin is said to take time to build up and do its job, I have sometimes wondered if that is really true, because sometimes its gastric discomfort side effects take little time at all in some people.

Hope you can get answers soon and get your BG numbers less crazy and controlled. Please ask all the questions you want, someone here may be able to better respond, related to experiences they have had.
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