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Question about Actos and Metformin with pre-diabetes.

5662 Views 7 Replies 3 Participants Last post by  onaughmae
Hello everyone.

In my introduction post I mentioned that I have a hard time sleeping at night. I get sweaty and achey and when I remove the blankets I become cold very quickly which makes me put the blankets on again and this starts an endless process throughout the night. My wife and kid sleep soundly saying the room temp is fine. Heck I used to sleep soundly year round before hitting my head.

Anyways. I am also still losing weight. I am eating pretty decent sized meals and snacks lately and still losing weight.

I wonder if the discomfort I feel at night is the body feeding off its own fat and or muscle. I always wake up with cold tingly hands, not just on the side I am sleeping either. Sometimes its in my feet.

I have been wanting to try metformin or actos to see if it relieves this night time aching.

I have heard though that metformin causes more weight loss and that actos athough it can cause weight gain causes bone fracture problems.

What is the opinion of those experienced here about these two meds?

I don't really want to make a daily routine of these meds but rather say one on monday, then one on wednesday, then one on saturday, just to see if it helps my sleeping problems. Maybe my body needs help absorbing at night?

Just guessing really. But I am willing to try anything since my sleeping problem is a month plus now and I am losing my mind and weight.

Thanks in advance for all thoughts. :)
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Hi Casey . . . I can't speak about Actos, but metformin doesn't work that way. It is a drug that builds up in your bloodstream, and then when it reaches maximum strength levels, the daily doses serve to maintain that maximum blood level. What it does is help with insulin resistance.
Ok, so I'd need to take like a 500 mg dose daily or something?

I am trying to figure out a light test dosage that would just help a little with insulin resistance.
Ok, so I'd need to take like a 500 mg dose daily or something?

I am trying to figure out a light test dosage that would just help a little with insulin resistance.
Have you checked your blood sugar when you wake up at night feeling sweaty, etc? Are you sure its a blood sugar issue causing this symptom? I have never had this symptom as part of my diabetes...only when I would go low occasionally. I have it sometimes now, but its a hormonal thing.
Have you checked your blood sugar when you wake up at night feeling sweaty, etc? Are you sure its a blood sugar issue causing this symptom? I have never had this symptom as part of my diabetes...only when I would go low occasionally. I have it sometimes now, but its a hormonal thing.
Yeah, it averages between 113-120 when I test when I wake up.

Which isn't the same as the sweatiness I get when I get up to 200.

It does feel like what women say is a "hot flash" during menopause. My mom is going through it now and says my description sounds just like the menopause hot flash.
Yeah, it averages between 113-120 when I test when I wake up.

Which isn't the same as the sweatiness I get when I get up to 200.

It does feel like what women say is a "hot flash" during menopause. My mom is going through it now and says my description sounds just like the menopause hot flash.
Yes, thats why I asked...sounds like hot flashes to me also. Your doctor could give you no explanation for this happening to you?
Yes, thats why I asked...sounds like hot flashes to me also. Your doctor could give you no explanation for this happening to you?
No. Actually my 4 doctors. My primary (who did the OGTT), my Gastro, Nephrlogist, Neurologist, can't find anything.

My mom, who is an RN 30 years now says my head injury may be causing the symptoms and that I may end up healing over 6-12 months or that it may not go away. Tomorrow I go in for one more round of blood tests with the nephrologist to see if pituitary,hypothalmus are still ok. He mentioned a few weeks ago that some times they get injured and don't show weird numbers in blood till months later. SO he wants to see how they are doing now 3 months in.

My whole interest in the metformin, Actos is the idea that my body is losing weight and that maybe because of insulin resistance.

But I am grasping at straws most of the time. I am at a point where I'll try anything to see if it lets me sleep without pain/aches. And I have tried a lot.

The strange thing is that diabetics don't usually report a tough time sleeping or napping especially after certain meals. My problem is sleep in general creates this ache/pain/sweat/chill after a few minutes of sleep and wakes me up.

I am on a mission to solve it. So forgive me if I ask tons of questions. :)

I just found out that cinnamon acts like insulin so I am trying the cinnamon today to see if it helps with sleeping tonight. 1/2 teaspoon with food.
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No. Actually my 4 doctors. My primary (who did the OGTT), my Gastro, Nephrlogist, Neurologist, can't find anything.

My mom, who is an RN 30 years now says my head injury may be causing the symptoms and that I may end up healing over 6-12 months or that it may not go away. Tomorrow I go in for one more round of blood tests with the nephrologist to see if pituitary,hypothalmus are still ok. He mentioned a few weeks ago that some times they get injured and don't show weird numbers in blood till months later. SO he wants to see how they are doing now 3 months in.

My whole interest in the metformin, Actos is the idea that my body is losing weight and that maybe because of insulin resistance.

But I am grasping at straws most of the time. I am at a point where I'll try anything to see if it lets me sleep without pain/aches. And I have tried a lot.

The strange thing is that diabetics don't usually report a tough time sleeping or napping especially after certain meals. My problem is sleep in general creates this ache/pain/sweat/chill after a few minutes of sleep and wakes me up.

I am on a mission to solve it. So forgive me if I ask tons of questions. :)

I just found out that cinnamon acts like insulin so I am trying the cinnamon today to see if it helps with sleeping tonight. 1/2 teaspoon with food.
No problem on the questions...just wish we could answer them all for you :) Do let us know what they find...I am really curious now as to what is causing it also :)
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